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    Home > Chemicals Industry > Chemical Technology > Comprehensively improve the level of vitamin D₃ technology - record the green synthesis technology of vitamin D3 series products of the first prize project of technological invention

    Comprehensively improve the level of vitamin D₃ technology - record the green synthesis technology of vitamin D3 series products of the first prize project of technological invention

    • Last Update: 2022-02-17
    • Source: Internet
    • Author: User
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    The green synthesis technology development and industrialization project of   vitamin D
    series products recently won the first prize of the 2021 China Petroleum and Chemical Industry Federation Technology Invention Award .
    The project was jointly completed by Zhejiang University of Technology, Zhejiang Garden Bio-Tech Co.
    , Ltd.
    , and Zhejiang Garden Nutrition Technology Co.
    ,

    Ltd.

      Vitamin D₃ series products, including VD₃ , 25- hydroxyVD₃ , 1α - hydroxyVD₃ , ,25-dihydroxyVD₃, are the drugs of choice for the treatment of osteoporosis and other diseases, with global sales of US$2.
    6 billion in 2020, Domestic sales of 1.
    8 billion yuan

    .
    The R&D and production of VD
    and 25-hydroxy VD is a worldwide problem, and the key technologies and markets have been monopolized by foreign companies for a long time
    .

      In order to solve the above problems, after 13 years of joint research, the project team pioneered a new synthesis process for 25-hydroxy VD , comprehensively improved the production process level of VD , and invented selective hydroxylation, air catalytic oxidation, reduction and dehydration, etc.
    key technology

    .
    Appraisal by an expert committee composed of academicians such as Tan Tianwei and Xu Chunming: the technology of the project is original, the overall technology and product quality have reached the international leading level, and it has significant economic and social benefits

    .

      The project has obtained 12 invention patents from China, the United States, Europe, Japan, etc.
    , and also won 2 Chinese Patent Excellence Awards, 1 China Petroleum and Chemical Industry Patent Gold Award, and 1 Zhejiang Province Patent Excellence Award

    .

    At present, the annual output of pure VD ₃  produced by Zhejiang Garden Group reaches 75 tons, with a global market share of 40%; the annual output of pure 25-hydroxy VD is 15.
    6 tons, making it the second company in the world and the first in China to produce 25-hydroxy VD
    Large-scale manufacturer, and become the only global supplier of DSM
    .

      In the past five years, the project has accumulated new sales of 1.
    86 billion yuan, profits of 750 million yuan, tax revenue of 310 million yuan, and export earnings of 178 million US dollars

    .



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