Crack the mystery of "mosquito dating" interference with hand-to-hand equipped with help green control mosquitoes

, Beijing, January 22 (Zheng Yingying) mosquito bites not only send "red envelopes" (red and swollen), but also spread malaria, dengue fever and other diseases. On January 22nd, a research team led by Wang Shibao of the China
Center for Excellence and Innovation in Molecular Plant Science published a paper entitled "Biological clock genes, lighting and ambient temperature co-regulation of malaria vectors by mosquito sexual information pigment synthesis, marriage and mating", which solves the mystery of mosquito "courtship" and helps mosquito control.
a wide variety of mosquitoes, common mainly by mosquito, Aedes aegypti mosquito and ku mosquito three major categories. Among them, according to mosquitoes, also known as malaria mosquitoes, mainly at night activities, is the vector of malaria.
Wang Shibao introduced, mosquitoes do not suck blood for a living, mosquitoes usually suck nectar and plant juice, female mosquitoes suck blood is to lay eggs to supplement nutrition.
the summer evening, mosquitoes mass, fly in the air and mate, a phenomenon known as "wedding flying".
study sheds light on the molecular mechanisms of "marriage fly" by mosquito clusters and the chemistry of male and female courtship. First, the researchers compared the expression of the head genes of the "wedding fly" and "unmarried fly" males collected in the wild, and found that the two biological clock core genes per and tim increased significantly in the head expression of the married male mosquito;
Further studies have found that the effects of light and temperature on "marriage fly" and mating by mosquitoes are achieved by regulating the expression of the biological clock gene per and tim, which reveals that the occurrence of "marriage fly" and mating by mosquitoes is coordinated by endo-biological clocks, external lighting and temperature signals.
as a "wedding fly" of the pressure axis play, male mosquitoes to female mosquitoes courting the chemical language "sex information", has previously been an open mystery. In this study, gene expression spectrum analysis found that the expression of gene desat1 in the "wedding fly" male mosquito significantly increased. Interference inhibits the expression of desat1, which also affects mosquito "marriage fly" and mating behavior. Further studies have found that the expression of desat1 is regulated by the biological clock gene per, tim and optical signals, and desat1 is involved in the synthesis of insect skin hydrocarbons, one of which is 27ane, the active ingredient of sexual information based on mosquitoes, thus revealing the mysteries of chemical communication by mosquito sex.
To test whether per, tim, and desat1 can also regulate the "marriage fly" and mating behavior of the African malaria vector, the Gambia Mosquito, Wang's research team and Professor Marcelo Jacobs-Lorena of Johns Hopkins University in the United States and Joel of the National Institutes of Health The Vega-Rodriguez team, working with the Diabate Abdoulaye research team at the Sant Institute of Science in Burkina Faso, West Africa, conducted outdoor testing in Bobo di Urasso, Burkina Faso, which confirmed that the core biological clock gene (per, tim) and gene desat1 have the same regulatory function in different mosquito "weddings" and mating.
This study promotes people's understanding of the mechanism of mating by mosquito "marriage fly" and mating, and also provides new methods for the development of mosquito green prevention and control technology (e.g., by manipulating mosquito "marriage fly" to interfere with mating or concentrated booby-trapping, the use of "sexual information" to enhance the sexual attraction and mating competitiveness of male mosquitoes in the wild, etc.), for the future to reduce mosquito control dependence on chemical pesticides, to achieve drug control mosquito control.