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CRAL: Comparison of treatment guidelines for pemphigus: systemic glucocorticoids, rituximab and other immunosuppressive therapies

 Last Update: 2021-10-20
 Source: Internet
 Author: User

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Pemphigus vulgaris (PV) and deciduous pemphigus (PF) are the two main clinical variants

Corticosteroid therapy

Corticosteroid therapy Corticosteroid therapy

Corticosteroid reduction in maintenance of remission

Corticosteroid reduction in the maintenance of remission period Corticosteroid reduction in the maintenance of remission period

Relapse/relapse cases

Relapse/Relapse CaseRelapse/Relapse Case

Anti-CD20 monoclonal antibody

Anti-CD20 monoclonal antibodyAnti -CD20 monoclonal antibody

Rituximab is used as a first-line drug for the treatment of moderate to severe pemphigus

Adjuvant immunosuppressant

Adjuvant immunosuppressant adjuvant immunosuppressant

Other therapies

Other therapies Other therapies

Literature source: Zhao W, Wang J, Zhu H, Comparison of Guidelines for Management of Pemphigus: a Review of Systemic Corticosteroids, Rituximab, and Other Immunosuppressive Therapies.
Clin Rev Allergy Immunol 2021 Aug 04

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