Crit Care: The relationship between serum uric acid, disease severity and outcome in COVID-19 patients

The severity of 2019 new coronary pneumonia ( COVID-19 ) varies from person to person, ranging from asymptomatic infection to acute respiratory distress syndrome that requires mechanical ventilation

Due to SARS-CoV-2 infection caused by renal proximal tubule dysfunction and accompanied by uric acid loss, a research article was published in Critical Care, an authoritative journal in the field of critical care medicine.

The researchers conducted a retrospective study using two independent cohorts to investigate and verify the prevalence, kinetics, and clinical relevance of hypouricemia in patients hospitalized with COVID-19 in a large teaching hospital in Brussels, Belgium

The discovery and verification cohorts included 192 and 325 patients hospitalized with COVID-19, respectively

It can be seen that in COVID-19 patients requiring hospitalization, low serum uric acid levels are common and are associated with the severity of the disease and progression to respiratory failure requiring invasive mechanical ventilation

Original source:

Inès Dufour.