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    Home > Biochemistry News > Biotechnology News > Curr Biol: Revealing the key role microspheres play in the development of diabetes

    Curr Biol: Revealing the key role microspheres play in the development of diabetes

    • Last Update: 2020-06-17
    • Source: Internet
    • Author: User
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    Photo Credit: Current Biology (2019)DOI: 10.1016/j.cub.2019.06.032pancreatic beta cells cannot release enough insulin to cope with the main marker of type 2 diabetes when blood sugar levels rise, and over the past 10 years, researchers have found that microspheres, as the skeleton of cells, play a key role in regulating the transport of insulin particles to cell membranes for secretion, and in this study, researcherS DrKathryn Trogden and others have found that microbiosynthetic particles are critical to micro-synthetic particlesresults have shown that glucose regulates the function of microspheres through the ubiquitous information molecule ring AMP and its effect protein EPAC2, where glucose signals promote the breakdown and reassembly of microspheres in the gorky body within the cell, where insulin particles formInhibition of EPAC2 blocks the formation of new Gorky-derived microtubes, eventually leading to the elimination of insulin particles in beta cellsconcluded that the results of this paper suggest that dynamic changes in regulating microspheres may be expected to help develop new potential treatments for diabetesoriginal origin of:Kathryn PTrogden et alRegulation of The UGongoe-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secrets Vesicle Biogenesis in The SpDOI: 10.1016/j.cub.2019.06.032
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