DDS: Will thin people also get liver fat degeneration?

We know that the incidence of obesity and non-alcoholic fatty liver disease (NAFLD) is increasing, and although liver fat degeneration is usually more likely to occur in obese patients, it remains to be seen whether liver fat lesions can also occur in lean meat patients who do not have typical risk factors.
, the researchers in this study aimed to determine the incidence and risk factors of liver fat degeneration in thin patients.
the researchers retrospectively collected thin patients with no viral hepatitis and a BMI of 25 kg/m2 for liver hardness measurement (LSM) and controlled attenuation parameters (CAP) using transient elastic imaging.
the study, 218 patients were included in the study, of whom 34.5% showed liver fatty degeneration (CAP-268 dB/m) and higher glutyl transpeptidease (GGT) in liver fatty degeneration patients (238.0 vs.112.1IU/mL; p= 0.013), AST (-63(±67.4)vs.38.5 (±32.9) IU / mL; p=0.001) and ALT (59.1 (±58.8)vs. 44.3 (±52.7) IU / mL; p s 0.048) was also higher and showed a trend towards more severe fibrosis (LSM 15.6 (±19.5)vs. 12.0 (±15.7) kPa; p=0.11 5), in the multiregression analysis, only serum uric acid levels were independently associated with liver fat degeneration (OR 1.43 / mg / dL per unit; 95% CI 1.001-2.054; p - 0.049).
14 patients (5.0%) died during an average follow-up period of 38.9 months.
patients with no fatty degeneration (98.7%) and fat degeneration (98.6%) had similar survival rates after one year without advanced fibrosis.
levels of serum uric acid increase the risk of liver fat degeneration in lean patients, the researchers concluded.
fibrosis rather than liver fat degeneration are risk factors for loss of survival in thin patients.
.