Dehydroandrographolide

Dehydroandrographolide

Dehydroandrographolide

【Structural formula】

【Molecular formula and molecular weight】C ₂₀ H ₂₈ O ₄ ;332.

[Source] The dry aerial part of Andrographis paniculata, a plant of the Acanthaceae family

【Properties】White crystals

This product is easily soluble in ethanol and acetone , soluble in chloroform , slightly soluble in benzene, and almost insoluble in water

Melting point: 202～204℃

【Purity Check】

TLC

1.

Developing solvent chloroform- ethyl acetate -methanol (4:3:0.

Inspection of 10% sulfuric acid ethanol solution, ultraviolet light (254nm) and inspection under sunlight

2.

Developing agent chloroform-acetone (1.

Inspection of 10% sulfuric acid ethanol solution, ultraviolet light (254nm) and inspection under sunlight

High performance liquid chromatography

Chromatographic column AgilentTC C ₁₈ , 5um (4.

The mobile phase methanol - water (60:40), 1ml / min

Detection wavelength 254nm

Differential calorimetry

Start temperature 50℃, end temperature 300℃, heating rate 5℃/min

[Structural identification] 250,207

3312, 3080, 1740, 1637, 885

EI-MS m/z: 332[M] ⁺

¹ H-NMR (CDCl ₃ ) δ: 0.

¹³ C-NMR (CDCl ₃ ) δ: 38.

【Storage】Dry and airtight
.