Deng potassium salt of L-p-hydroxyphenylglycine (four)

4.

4.

4.

4.

4.

Weigh 2.

Take the arithmetic mean of the two parallel determination results as the determination result, and the absolute difference between the two parallel determination results shall not exceed 0.

4.

4.

The supernatant of the sample suspension is spotted on one end of the silica gel plate, and the developing agent spreads from one end of the silica gel plate to the other end by capillary action, during which the free p-hydroxyphenylglycine is separated

4.

4.

4.

2 4.

4.

4.

4.
10.
3 Analysis steps

Weigh 0.
2g laboratory sample, accurate to 0.
0001g
.
Add 10ml of developing agent 1, the solution is suspended, after the precipitate settles, take 2μL of the supernatant and spot on the silica gel plate, and spot 2μL of the standard solution near this point (equivalent to the sample containing p-hydroxyphenylglycine with a mass fraction of 0.
5 %), spread out about 5cm with spreading agent 1 and dry in the air, then spread about 9cm with spreading agent 2, after drying in a (100±2)℃ drying oven for 5 minutes, spray with benzopenteryl alcohol solution, Continue to dry in a drying oven at (100±2)°C for 2 minutes
.
Observe the spot color of the sample solution and the standard solution.
The spot color of the sample solution should not be darker than the spot color of the standard solution
.

5 Inspection rules

5.
1 Inspection classification

Inspection is divided into factory inspection and type inspection
.

5.
1.
1 Factory inspection

The factory inspection items are the appearance, identification test, mass fraction of L-p-hydroxyphenylglycine Deng potassium salt, specific rotation, mass fraction of loss on drying, absorbance and pH value specified in 3 requirements, which should be inspected batch by batch
.

5.
1.
2 Type inspection

Type inspection items are all items specified in Table 1
.
Under normal production conditions, type inspection shall be carried out at least once every three months
.

Type inspection should also be carried out in one of the following situations
.

a) Update key production processes
.

b) The main raw materials have changed
.

c) Production was stopped and resumed
.

d) There is a big difference between the factory inspection results and the last type inspection
.

e) Contract stipulations
.

5.
2 Batch

The product is a batch of homogeneous products produced by the same reaction tank at one time
.

5.
3 Sampling

Sampling according to the provisions of GB/T6678-2003 and GB/T6679-2003, the sampling volume is not less than 200g, divided into 2 clean, dry ground-mouth bottles, labelled, indicating the product name, batch number or production date And the name of the sampler
.
One bottle is used for inspection, and the other bottle is used as a reserve sample and kept for six months for future reference
.

5.
4 Judgment rules and reinspection

L-p-Hydroxyphenylglycine Deng potassium salt is inspected by the quality inspection department of the manufacturer in accordance with the provisions of this standard, and the manufacturer shall ensure that the products shipped out of the factory meet the requirements of this standard
.
Each batch of products that leave the factory should be accompanied by a quality certificate in a certain format, which includes: the name of the manufacturer, the name of the product, the product grade, the batch number or the date of production, and the number of this standard
.

The test result is judged according to the rounding value comparison method in GB/T1250
.
If one of the inspection results does not meet the requirements of this standard, samples should be taken from twice the amount of packaging units for re-inspection.
Even if only one indicator does not meet the requirements of this standard, the entire batch of products will be unqualified
.

6 Marking, packaging, transportation and storage

6.
1 Logo

There should be a firm and obvious mark on the packaging, which includes the product name, manufacturer name, factory address, telephone number, net content, trademark, batch number or production date, shelf life, number of this standard, storage precautions and requirements specified in GB/T191-2000 "Fear of the sun" and "fear of rain" signs
.

6.
2 Packaging

6.
2.
1 The L-p-Hydroxyphenylglycine Deng Potassium Salt is packaged in three layers, the inner and middle packages are black polyethylene plastic film bags, and the outer package is kraft paper bags lined with white plastic film
.

6.
2.
2 When packing, tie the middle and inner plastic bags with packing ropes respectively, and seal the outer packing with a sealing machine
.
The export packaging form can be selected according to user requirements
.

6.
2.
3 The net content of each bag (or barrel) is 25kg, or it can be packaged according to user requirements
.

6.
3 Transportation

L-P-Hydroxyphenylglycine Deng potassium salt products should be protected from sunlight, rain, and corrosive substances during transportation
.

6.
4 Storage

L-P-Hydroxyphenylglycine Deng potassium salt should be stored in a cool and dry warehouse
.

Under the packaging, transportation and storage conditions in accordance with this standard, the shelf life of L-p-hydroxyphenylglycine Deng potassium salt is 6 months from the date of production
.
After the expiry date, the product can be re-inspected according to this standard.
If the test result meets the requirements of this standard, the product can still be used
.