Denmark has successfully used genetic tools to produce 50 cytochrome P450 enzymes of E. coli that can be used to synthesize anti-cancer drugs.

Danish researchers have reported that they have successfully used E. coli to produce a class of important bioactive substances, cytochrome P450, the technology is expected to be used in the mass production of anti-cancer drugs such as yew alcohol.
the results were carried out in collaboration with researchers from the Centre for Bio sustainability of the Danish Noor and Nord Foundation and the University of Copenhagen, and the paper was published in the new issue of the American Journal of Biotechnicals and Bioengineering.
cytochrome P450 is a class of enzymes that play an important role in biomebolism, and previous studies have shown that some of these members can be used to synthesize active ingredients in anticancer drugs such as yew alcohol.
some plants can use cytochrome P450 to synthesize a variety of "chemical weapons" to protect against pests and diseases and harsh environments.
but the plant itself can only produce trace cell pigment P450, and the extraction process is complex and susceptible to contamination.
, some of the plants involved are endangered and cannot be used in industrial production.
Danish researchers developed a genetic tool that successfully produced about 50 cytochrome P450 enzymes from E. coli of different strains, including varieties that can be used to synthesize the anti-cancer drugs yew alcohol and giant tercol.
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