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    Home > Active Ingredient News > Antitumor Therapy > Dermatology: Ultrasound identification of morphological features and thickness of basal cell carcinoma of the skin

    Dermatology: Ultrasound identification of morphological features and thickness of basal cell carcinoma of the skin

    • Last Update: 2022-04-23
    • Source: Internet
    • Author: User
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    Basal cell carcinoma (BCC) is one of the most common skin tumors, most basal cell carcinomas occur in the head and neck, and although they rarely metastasize (<0.
    1%), they can be locally aggressive and have high recurrence rate
    .


    Pathological biopsy remains the gold standard for diagnosis; however, with the development and increasing use of topical, intralesional, photodynamic, laser, and radiation therapy, and more recently hedgehog inhibitors, non-invasive diagnostic methods may be challenged favor


    High-frequency ultrasound (e.
    g.
    , ≥15 MHz) has high definition and penetrability, and can produce clear images, so it is considered a first-line imaging technique for the evaluation of non-melanoma skin cancers
    .


    Basal cell carcinoma appears on ultrasound as a hypoechoic dermal or subdermal structure of various shapes, often containing tumor hyperechoic spots


    The purpose of this article was to evaluate the performance of high-frequency ultrasound in assessing BCC in order to develop recommendations for its use and to conduct a systematic review of the relevant literature
    .


    Central, Medline, Embase, CINHAL and Web of Science were searched by computer using the search terms "B-ultrasound" and "Basal Cell Carcinoma" (January 2005-December 2020)


    High-frequency ultrasound provides accurate depth measurements, especially for BCCs >1 mm
    .


    The definition of the in vivo medial margin requires further study; however, the in vitro margin assessment seems convincing


    Overall, high-frequency ultrasound accurately assessed the depth of the BCC
    .


    Among studies that specifically compared ultrasound depth and histopathology, 6/7 studies reported a moderate to high correlation


    Source: Laverde-Saad A, Simard A, Nassim D,, Performance of Ultrasound for Identifying Morphological Characteristics and Thickness of Cutaneous Basal Cell Carcinoma: A Systematic Review.


     

     

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