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Dev Cogn Neurosci: Adolescent alcohol use disorder and cannabis use disorder symptoms are related to neural prediction error signals and responses to novelties

 Last Update: 2021-04-13
 Source: Internet
 Author: User

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The two most common illegal substances used by teenagers are alcohol and marijuana.

151 teenagers participated in this task while receiving functional magnetic resonance imaging (fMRI).

The AUD Discrimination Test ( AUDIT ) compares the proportion of trials with the highest EV non-novel stimulus selected .

The main effects of AUDIT on dlPFC/iFG ( A ), dlPFC (B) , aIC ( C ) and ventral nucleus ( D ).

The first goal of the study was to investigate the correlation between AUD/CUD symptom levels and RPE signals.

All in all, the AUDIT score is negatively correlated with the RPE signals in the ventral putamen, iFG, dlPFC, and iPL.

The AUDIT score was negatively correlated with the RPE signals in the ventral putamen, iFG, dlPFC, and iPL.

Keywords: adolescent; alcohol use disorder; computational model; reward prediction error; striatum; functional magnetic resonance imaging.

Original source:

Aloi, Joseph et al.

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