Development direction of continuous production mode or solid preparation industry in the next five years

[market analysis of pharmaceutical network] solid preparations are widely used and have a large number of varieties in pharmaceutical preparations, and occupy an important share in pharmaceutical preparations In recent years, the rapid development of the domestic pharmaceutical industry has driven the growth of the total output value of the domestic pharmaceutical industry At the same time, it also brings opportunities to the domestic solid preparation equipment enterprises with advantages However, with the continuous promotion of medical reform policy and the rising cost, solid preparation manufacturing enterprises are under great pressure Solid preparation manufacturing equipment enterprises need to develop in a more efficient, economic and flexible direction Not long ago, the relevant person in charge of pharmaceutical machinery enterprises said in an interview with pharmaceutical.com that continuous production mode is the development mode that the company has been exploring and practicing now and in the future "In the next five years or so, this model may become a development direction that the industry needs to study, such as solid preparations and injections." It is understood that continuous production is the process of product manufacturing, which needs to be closely linked before and after production That is to say, from the time when the raw materials are put into production to the time when the finished products are made, each process shall be carried out continuously according to the process requirements In recent years, with the advent of intelligent era, the rise of big data is promoting industrial transformation and upgrading, and continuous production mode has been widely used in metallurgy, textile, chemical and other industries Compared with the traditional mass production mode, the continuous production mode has obvious advantages In the pharmaceutical industry, the continuous production can help the pharmaceutical production to develop in the direction of intelligence, realize more efficient and flexible production, control the production cost for pharmaceutical enterprises, so as to help develop more drugs with low price and better efficacy, and benefit patients The author understands that in order to help the solid preparation enterprises to achieve continuous production and promote industrial innovation and development, the domestic solid preparation equipment enterprises represented by large-scale enterprises are starting to develop and layout new technologies For example, solid pharmaceutical equipment manufacturing enterprises provide innovative solutions for the continuous production of solid pharmaceutical and pave the way for more efficient drug production "From powders to tablets and capsules, our focus is on technology and services that allow our customers to develop, produce and package their products flexibly," said the company's head Our highlight is to be able to move products from mass production to continuous production " Some enterprises have also invested in the construction of intelligent solid preparation equipment project of traditional Chinese medicine, which is used for the production of five dosage forms, including capsule, tablet, granule, soft capsule and pill It is reported that the project can produce 6 billion 500 million capsules per year, 1 billion 300 million capsules of soft capsules, 3 billion 300 million tablets of Chinese medicine tablets, 2400 tons of granules, 273 tons of pills, 1 billion tablets of chemical tablets, 110 million capsules of chemical drugs, 220 million adhesive patches and 50 million 50 million gels At the same time, raw and auxiliary materials, packaging materials storage and transportation, preparation production, finished products warehousing and other links will realize flow, continuity, automation and standardization Since this year, with the continuous promotion of the volume procurement policy, solid preparation enterprises, especially bid winning enterprises, are facing great challenges in cost control and how to ensure production capacity and quality, and continuous production mode may become a new research and development direction At the recent cross enterprise intelligent manufacturing exchange meeting, 4 + 7 pharmaceutical companies winning the bid for volume procurement shared their experience in continuous manufacturing and discussed the continuous production mode of solid preparations It is reported that the pharmaceutical company has accumulated rich experience in the field of continuous manufacturing and intelligent manufacturing, and is continuously exploring to build a large-scale and green Lean Factory, which will reduce cost input through scale effect and lean production, so as to ensure the stability of product quality, price and supply.