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    Home > Food News > Food Articles > DHA treats brain damage caused by stroke better than EPA

    DHA treats brain damage caused by stroke better than EPA

    • Last Update: 2021-02-18
    • Source: Internet
    • Author: User
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    DHA
    can be α
    -
    by synthesized from flaxseed acid or obtained from breast milk, fish oil, and dietary supplements.
    ©iStockA recent study from Columbia University found that

    -3
    unsaturated fatty acids can reduce brain damage caused by stroke.currently, treatments for brain damage use triglyceride emulsions containing 22 carbon hexaenelic acid (
    DHA
    )
    w
    -3
    unsaturated fatty acids. A recent study published in
    Plos One
    found that this treatment reduces oxidative damage to the brain in the short and long term and promotes neuron production. Twenty-carbon pentagonic acid (
    EPA
    ) has a weaker effect.Harry Rice
    , vice president of management and scientific affairs atGlobal
    EPA
    and
    DHA -3
    ,
    GOED
    ), said:
    "These studies provide pristine evidence of the protective effects of
    DHA
    on neurons after local isemia in the brain, but there is still a lot of research to support this.

    -3
    unsaturated fatty acids protect neurons when attacked.
    Richard Deckelbaum
    , director of the Nutrition Association at Columbia University Medical Center in New York and a professor of epidemiology and co-author of theMethodologystudy, described the experiment by selecting mice
    10
    days old for the treatment of local isotrophic (
    HI
    ) injuries in the brain.such injuries are the exposure of the brain to deadly low concentrations of oxygen (hypoxia) and
    /
    or a significant reduction in the brain's blood supply (local ischemia) to mimic stroke conditions.The experimental mice were treated for hypoxic local ishemosis brain damage
    ©iStock/MarquesPhotographyand then injected with an emulsion containing
    DHA
    or
    EPA
    through celiac injections.HI
    injection immediately after the end of the injury and a second shot an hour later. Inject common physiological saline (
    Veh
    ) as a control group. The three groups of mice were tagged as follows:
    HI-Veh
    ;
    HI-EPA
    ;
    HI-DHA
    .restore the brain's blood supply.
    4-5
    , the composition of mitochondrial fatty acids and the buffering capacity of calcium ions (
    Ca
    2 plus
    ) were detected.loss of mitochondrial function is considered to be one of the mechanisms that occur after a stroke. After the recovery of blood flow, the mitochondrials appear
    Ca
    2 plus
    overload phenomenon, resulting in increased mitochondrial membrane permeability, energy generation stopped, inducing apoptosis of cells.researchers evaluated the nervous system function of mice at
    24
    hours,
    8
    weeks, and
    9
    at three points in time for brain damage.at
    24
    hours, the
    damage
    mice treated with DHA was significantly reduced. However
    mice
    treated with EPA did not have a similar effect. over the next few weeks, the brain function of mice treated with
    DHA
    was better than that of mice treated with
    EPA
    and in the control group. DHA
    high levels of DHA in mitochondrials
    the
    the DHA. " In our current and prior studies on the neuropulation of
    w
    -3
    unsaturated fatty acids, we found that
    -3
    fatty acids were good for mice's resistance and safety. Dr
    Deckelhaum said
    . now, we need to do more research on
    DHA
    's 'safety parameters' for animals before conducting human trials," he said. Like other new treatments, we need to go through a series of necessary steps before we can get registration approval. The of this article is
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