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Gene - diet interactions are defined as the effects of gene and diet exposure on disease outcomes.
Gene - diet interactions are defined as the effects of gene and diet exposure on disease outcomes.
The current dietary guidelines on the prevention and management of T2D emphasize the adoption of an overall healthy diet, rather than focusing on individual nutrients or single foods .
The current dietary guidelines on the prevention and management of T2D emphasize the adoption of an overall healthy diet, rather than focusing on individual nutrients or single foods .
To explore this question, this study specifically evaluated the quality of the diet and the occurrence of type 2 diabetes (T2D To explore this question, this study specifically evaluated the quality of the diet and the development of type 2 diabetes (T2D diabetes mutual between genetic susceptibility) of Role
Demographic characteristics of participants classified by quartile of diet quality scores in the current UK Biobank
It was found that there was a significant negative correlation between GRS and diet quality score
There is a significant negative correlation between GRS and diet quality score
T2D and HbA1c levels HRs classified by the combination of diet quality score and GRS
T2D and HbA1c levels HRs classified by the combination of diet quality score and GRSIn summary, this study found that the protective association between diet quality and T2D and blood HbA1c changed due to genetic risk
Individuals with higher genetic risk, especially those with extremely high genetic risk, may benefit more by adhering to a healthy diet in T2D prevention
References: Effect of Diet Quality and Genetic Predisposition on Hemoglobin A1c and Type 2 Diabetes Risk: Gene-Diet Interaction Analysis of 357,419 Individuals .
Diabetes Care 2021 Nov; 44(11): 2470-2479.
https://doi.
org/ 10.
2337/dc21-1051 Effect of Diet Quality and Genetic Predisposition on Hemoglobin A1c and Type 2 Diabetes Risk: Gene-Diet Interaction Analysis of 357,419 Individuals https://doi.
org/10.
2337/dc21-1051
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