Diabetes Care: Relationship between early hospitalization of blood sugar fluctuations and death in patients with neo-coronary pneumonia

In a recent study published in Diabetes Care, an authoritative journal in the field of diabetes, researchers looked at the relationship between early blood sugar control and adverse outcomes in hospitalized patients with COVID-19 in Wuhan, China.
the study, a large case series, researchers obtained data on COVID-19 patients who were hospitalized continuously at Wuhan City Central Hospital between January 2 and February 15, 2020, and included all patients with defined outcomes (death or discharge).
researchers extracted demographic indicators, clinical, therapeutic and laboratory information from the subjects' electronic medical records.
researchers collected daily data on peresacose blood sugar from the first week of the subject's hospitalization to determine blood sugar status and fluctuations,as measured by the square root of the variance in daily perks.
the study included 548 patients (with a medium age of 57; 298 women and 99 diabetics), 215 patients with acute respiratory distress syndrome (ARDS), with 489 survivals and 59 deaths.
patients with higher average blood sugar levels in the first week of hospitalization were older, with a higher probability of complications and laboratory indicators, longer hospital stays, higher costs, and a higher risk of developing severe pneumonia, ARDS and death.
compared to patients with the lowest four-digit fluctuations in blood sugar, patients with the highest swings had an increased risk of ARDS (risk ratio of 1.97 (95% CI of 1.01, 4.04)) and death (risk ratio of 2.73 (95% CI of 1.06,7.73).
results may be instructive for optimizing blood sugar control strategies in patients with COVID-19 in the early stages of hospitalization.