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A recent study published in Diabetes Care, an authoritative journal in the field of diabetes, aims to assess the link between severe hypoglycemia and cardiovascular disease (CVD) measured at baseline in older diabetics living in the community.
researchers included older diabetics from the Community Atherosclerosis Risk Study (ARIC), who participated in the fifth visit (baseline 2011-2013).
severe hypoglycemia at baseline is defined as the use of the first ICD-9 code in hospitalization, emergency care, and ambulance calls.
researchers assessed the cross-sectional association between severe hypoglycemia and the function of the heart structure of the echo cardiac chart, and used negative heliodes and Cox regression models to proactively assess the risk of CVD (coronary heart disease, stroke, or heart failure) and total cause mortality from baseline to December 31, 2018.
of the 2,193 participants (the average age of the SD was 76 , 57 percent were women and 32 percent were blacks), 79 had a history of severe hypoglycemia at baseline.
severe hypoglycemia and reduced left-chamber blood test score (β coefficient adjusted for -3.66% (95% CI is -5.54 to -1.78)), higher left-chamber lysed end-stage volume (14.80 mL (95% CI is 8) .77 to 20.84), higher E/A ratio (0.11 (95% CI is 0.03 to 0.18)) and higher interval E/e' (2.48 (95% CI is 1.13, 3.82) related.
the corrected model, the occurrence of severe hypoglycemia without CVD was associated with the occurrence or recurrence of CVD (the rate of occurrence was 2.19 (95% CI was 1.24 to 3.88) and the all-cause mortality rate (risk ratio was 1.71 (95% CI was 1.10 to 2.67).
, the history of severe hypoglycemia is associated with changes in heart function and is an important marker of future cardiovascular risk in older adults.