Diabetes Care: Risk factors for resting heart rate and its relationship with cardiovascular disease

And without diabetes compared to individuals with diabetes a higher resting heart rate, which may be long-term medsci.
cn/course/search.
do?w=%E5%BF%83%E8%A1%80%E7%AE%A1">heart blood vessels have predictive value disease (CVD) risk.

Recently, a research article was published in Diabetes Care, an authoritative journal in the field of diabetes.
Researchers used data from the DCCT/EDIC study to evaluate whether intensive and conventional hypoglycemic treatments have a protective effect on heart rate, and evaluated whether the mediation treatment group has a protective effect.
The factors of heart rate difference between the two and the influence of heart rate on future CVD risk.

The researchers evaluated the longitudinal changes in the annual ECG heart rate of 1402 type 1 diabetic participants during a 22-year follow-up period.
The linear mixed model is used to evaluate the effect of the treatment group on the average heart rate that changes over time, while the Cox proportional hazard model is used to evaluate the effect of heart rate on the risk of CVD.

52% of the participants were male, the average age ± SD was 33 ± 7 years, the duration of diabetes was 12 ± 5 years, and the HbA1c of the intensive and conventional hypoglycemic treatment groups were 7.
4 ± 1.
2% and 9.
1 ± 1.
6%, respectively.
Compared with the conventional hypoglycemic treatment group, the heart rate of participants in the intensive hypoglycemic treatment group was significantly lower.
Although significant differences in the subject's heart rate can be completely eliminated by the average HbA1c, a higher heart rate can predict CVD and major adverse cardiovascular events without being affected by other risk factors.

It can be seen that after 22 years of follow-up, compared with conventional hypoglycemic therapy , intensive hypoglycemic therapy is still significantly correlated with lower heart rate.
This is consistent with the new efficacy of intensive hypoglycemic therapy for long-term protection of CVD .
The difference in the effect of the treatment groups on the heart rate can be explained by the difference in the average HbA1c.
Original source: Sareh Keshavarzi, et al.
org/10.
2337/dc20-2387" target="_blank" rel="noopener">Risk Factors for Longitudinal Resting Heart Rate and Its Associations With Cardiovascular Outcomes in the DCCT/EDIC Study .
Diabetes care.
2021.
https://doi.
org/10.
2337/dc20-2387

org/10.
2337/dc20-2387" target="_blank" rel="noopener">