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Diabetes Care: The relationship between body fat distribution and non-alcoholic fatty liver in adult patients with type 1 diabetes

 Last Update: 2021-06-16
 Source: Internet
 Author: User

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Obesity associated with non-alcoholic fatty liver (NAFL) has increased in patients with type 1 diabetes
.

Recently, a research article was published in Diabetes Care, an authoritative journal in the field of diabetes, in which researchers aimed to explore the relationship between fat distribution and NAFL in this population

Non-alcoholic fatty liver diabetes

The study included 121 adult patients with type 1 diabetes from the FinnDiane study .
NAFL was determined by magnetic resonance imaging
.

Body composition is evaluated by DXA examination

Type 1 diabetes

Researchers used Logistic regression to explore the relationship between body fat distribution, waist circumference to height ratio (WHtR), BMI and NAFL
.

Receiver operating characteristic (ROC) curves are used to determine the thresholds of WHtR and BMI to determine the highest sensitivity and specificity for detecting NAFL

ROC curve

The median age of the subjects was 38.
5 (33-43.
7) years, the duration of diabetes was 21.
2 (17.
9-28.
4) years, 52.
1% were women, and the prevalence of NAFL was 11.
6%
.

After adjusting for gender, age, course of diabetes and PNPLA3 rs738409, the volume (P=0.

It can be seen that there is a correlation between visceral adipose tissue and NAFL in adults with type 1 diabetes.
When screening for NAFL in this population, WHtR can be considered
.

There is a correlation between NAFL visceral adipose tissue in adults with type 1 diabetes in this population screening when NAFL, consider WHtR screening the original source: at The Relationship Body Fat Distribution's and the Between Nonalcoholic Fatty Liver in Adults With Type 1 Diabetes in This message

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