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Diabetes Care: The relationship between type 2 diabetes and abnormal brain structure, cognitive ability, and risk of dementia

 Last Update: 2021-11-12
 Source: Internet
 Author: User

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Cognitive dysfunction is increasingly recognized as an important clinical complication of type 2 diabetes (T2D)

The risk of dementia in

Compared with the general population, T2D patients with various risk factors within the recommended target range (such as non-smokers; as well as glycosylated hemoglobin, cholesterol , blood pressure, BMI, albuminuria, physical activity and diet levels recommended by the guidelines ) have almost no excess deaths or heart vascular disease risk

The prospective data comes from 87856 people (n=10663 diabetic patients, n=77193 control subjects; baseline 2006-2010) from the British Biobank, who were followed up for dementia until February 2018

After an average follow-up of 9.

Compared with the control group (incidence rate 0.

Compared with the control group, the number of risk factors within the target range of HR for dementia occurred

Similarly, when there are many target risk factors, the differences in processing speed, executive function, and brain volume gradually become smaller

Conclusion In diabetic patients, the risk of excess dementia, lower cognitive performance, and brain abnormalities gradually decreases with the increase in the number of target risk factors

references:

Association of Type 2 Diabetes, According to the Number of Risk Factors Within Target Range, With Structural Brain Abnormalities, Cognitive Performance, and Risk of Dementia.

Association of Type 2 Diabetes, According to the Number of Risk Factors Within Target Range, With Structural Brain Abnormalities, Cognitive Performance, and Risk of Dementia.

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