We aim to characterize temporal trends and correlations in glycemic control in adolescents and young adults (YYA) with youth-onset diabetes
The study included 6369 people with type 1 or type 2 diabetes from the Diabetic Young Adult Study
Participant visit data were divided into time periods 2002-2007, 2008-2013 and 2014-2019, diabetes duration was divided into 1-4, 5-9 and ≥10 years, and 1-9, 10-14, 15 - Age groups of 19, 20-24 and ≥25 years old
The researchers used a multivariate regression model to assess differences in hemoglobin A1c (HbA1c) over time in different types of diabetes
Models were adjusted for location, age, sex, race/ethnicity, household income, health insurance status, insulin regimen, and duration of diabetes, with aggregate and stratified analyses for each duration of diabetes and age group
The adjusted mean HbA1c of the type 1 diabetes YYA cohort from 2014 to 2019 was 8.
Glycemic control of type 1 diabetes YYA in the 10-14, 15-19, and 20-24 age groups in the 2014-2019 cohort was worse than in the 2002-2007 cohort
Race/ethnicity, household income, and treatment regimen predicted differences in glycemic control among participants with type 1 diabetes in the cohort from 2014-2019
Adjusted mean HbA1c for type 2 diabetes YYA during 2014-2019 was 8.
Compared with the 2008-2013 cohort, participants with type 2 diabetes aged ≥25 years had poorer glycemic control
Only treatment regimen was associated with differences in glycemic control among participants with type 2 diabetes
CONCLUSIONS: Despite great advances in diabetes detection technology, drugs, and more aggressive hypoglycemic targets, many current YYAs are less likely to achieve desired levels of glycemic control than earlier cohorts
Trends in Glycemic Control Among Youth and Young Adults With Diabetes: The SEARCH for Diabetes in Youth Study.
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