We aim to characterize temporal trends and correlations in glycemic control in adolescents and young adults (YYA) with youth-onset diabetes
.
The study included 6369 people with type 1 or type 2 diabetes from the Diabetic Young Adult Study
.
Participant visit data were divided into time periods 2002-2007, 2008-2013 and 2014-2019, diabetes duration was divided into 1-4, 5-9 and ≥10 years, and 1-9, 10-14, 15 - Age groups of 19, 20-24 and ≥25 years old
.
The researchers used a multivariate regression model to assess differences in hemoglobin A1c (HbA1c) over time in different types of diabetes
.
Models were adjusted for location, age, sex, race/ethnicity, household income, health insurance status, insulin regimen, and duration of diabetes, with aggregate and stratified analyses for each duration of diabetes and age group
.
The adjusted mean HbA1c of the type 1 diabetes YYA cohort from 2014 to 2019 was 8.
8±0.
04%
.
Glycemic control of type 1 diabetes YYA in the 10-14, 15-19, and 20-24 age groups in the 2014-2019 cohort was worse than in the 2002-2007 cohort
.
Race/ethnicity, household income, and treatment regimen predicted differences in glycemic control among participants with type 1 diabetes in the cohort from 2014-2019
.
Adjusted mean HbA1c for type 2 diabetes YYA during 2014-2019 was 8.
6±0.
12%
.
Compared with the 2008-2013 cohort, participants with type 2 diabetes aged ≥25 years had poorer glycemic control
.
Only treatment regimen was associated with differences in glycemic control among participants with type 2 diabetes
.
CONCLUSIONS: Despite great advances in diabetes detection technology, drugs, and more aggressive hypoglycemic targets, many current YYAs are less likely to achieve desired levels of glycemic control than earlier cohorts
.
.
Original Source:
Faisal S.
Malik.
et al.
Trends in Glycemic Control Among Youth and Young Adults With Diabetes: The SEARCH for Diabetes in Youth Study.
Diabetes care.
2022.
https://diabetesjournals.
org/care/online-ahead- of-print
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