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Background: In 2015, there were an estimated 415 million people with diabetes worldwide, and the number is projected to rise to 642 million
Objective: There is limited evidence on the relationship between vitamin D status and microvascular complications in individuals with type 2 diabetes mellitus (T2D), of which vitamin D deficiency or insufficiency is particularly common
Study design and methodology: This analysis included 14,709 patients with
Results: The median serum 25(OH)D concentration was 40.
Table 1 Serum 25(OH)D concentrations of different VDR genotypes in T2D patients in the UK Biobank
Table 2 Multivariate correction risk ratio (95% CIs) in the association between VDR polymorphisms and diabetes microvascular complications in patients with T2D in the UK Biobank
Table 3 Risk ratio of multivariate correction for the relationship between serum 25(OH)D concentration and diabetic microvascular complications in patients with T2D (95% CIs) according to different genotypes of VDR polymorphisms
Conclusion: Higher serum 25(OH)D concentrations are significantly associated
Source: Chen X, Wan Z, Geng T,et al.