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Diabetes: Long-term effects and clinical predictors of acute kidney injury on the progression of diabetic nephropathy in Chinese patients with type 2 diabetes

 Last Update: 2022-04-21
 Source: Internet
 Author: User

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Diabetic nephropathy (DKD) , especially type 2 diabetes (T2D), isthe most common cause of end-stage renal disease (ESRD) and is associated with an increased risk of cardiovascular disease and premature death.

Different clinical factors are known to be associated with AKI, including hypovolemia, diuretic use, and CKD

To assess the long-term impact of acute kidney injury (AKI) on the progression of diabetic nephropathy (DKD) and all-cause mortality, and to investigate the determinants of AKI in Chinese patients with type 2 diabetes (T2D)

Polygenic Risk Score (PRS)

Validation was sought in an independent cohort of 6007 patients (age 61.

Identifying serum uric acid as a modifiable risk factor and PRS as an unmodifiable risk factor may help to identify high-risk individuals for the prevention of acute renal failure and its long-term impact on T2D

Source: Jiang G, Luk AO, Tam CHT, et al.
Clinical Predictors and Long-term Impact of Acute Kidney Injury on Progression of Diabetic Kidney Disease in Chinese Patients With Type 2 Diabetes.
Diabetes.
2022;71(3):520 -529.
doi:10.
2337/db21-0694 Jiang G, Luk AO, Tam CHT, et al.
Clinical Predictors and Long-term Impact of Acute Kidney Injury on Progression of Diabetic Kidney Disease in Chinese Patients With Type 2 Diabetes.
Diabetes.
2022 ;71(3):520-529.
doi:10.
2337/db21-0694

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