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    Home > Active Ingredient News > Endocrine System > Diabetes Metab Res Rev: TIR is negatively correlated with amputation and all-cause mortality in hospitalized patients with diabetic foot ulcers

    Diabetes Metab Res Rev: TIR is negatively correlated with amputation and all-cause mortality in hospitalized patients with diabetic foot ulcers

    • Last Update: 2021-10-20
    • Source: Internet
    • Author: User
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    Diabetic foot ulcer (DFU) is one of the most serious complications of diabetes


    diabetes

    With the advancement of dynamic blood glucose monitoring (CGM) technology and the increase in applications, researchers have revealed some specific indicators in the overall blood glucose control assessment based on consensus statements issued by several organizations


    consensus

    This study evaluated the correlation between time within range (TIR) ​​and amputation and all-cause mortality in hospitalized patients with diabetic foot ulcer (DFU)


    Materials and Method

    Materials and methods Materials and methods

    A retrospective analysis of 303 DFU inpatients


    result

    Result result

    Of the 303 patients enrolled, 50 (16.


    Both amputation and all-cause mortality decreased with the increase of TIR quartile.


    Figure 1

    (A) Calculate the average percentage of blood glucose readings, p-values, of all participants in each group that fall within the specified range by t-test


    (B) The percentage of amputation and all-cause mortality were calculated by TIR quartiles, and the p trend value was calculated by ANOVA and linear polynomial comparison


    Both amputation and all-cause mortality are negatively correlated with TIR

    Both amputation and all-cause mortality are negatively correlated with TIR

    Figure 2 : Spearman correlation coefficient between blood glucose indicators


    Figure 2

    The results showed that some blood glucose indicators were highly correlated (MBG and grade 2 TAR were 0.


    The results showed that some blood glucose indicators were highly correlated (MBG and grade 2 TAR were 0.


    in conclusion

    Conclusion conclusion

    Among patients with DFU during hospitalization, TIR was strongly negatively correlated with amputation and all-cause mortality


    Among patients with DFU during hospitalization, TIR is strongly negatively correlated with amputation and all-cause mortality

     

    Original link: https://pubmed.


    https://pubmed.


    2021 Sep 29;e3498.
    doi: 10.
    1002/dmrr.
    3498.

     



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