Diabetes Obes Metab: The relationship between obesity in people with type 2 diabetes and severe COVID-19 outcomes.

Obesity and diabetes have been identified as common severe COVID-19-related complications.
, researchers aim to assess the relationship between BMI classification and early COVID-19 prognosis in patients with type 2 diabetes (T2D) inpatients, according to a recent study published in Diabetes Obesity and Metabolism, an authoritative journal in the field of metabolic endocrine diseases.
the researchers analyzed T2D patients in four BMI subgroups according to the World Health Organization classification.
the clinical characteristics of the subjects and coVID-19-related outcomes (i.e., mechanical intage (IMV), death on day 7 and discharge from hospital) were analyzed based on BMI status.
of 1965 T2D patients, the researchers compared 434 (22.1%) normal weight (18.5-24.9 kg/m2, reference group), 726 (36.9%) overweight (25-29.9 kg/m2) and The analysis was carried out on 805 (41.0%) obese subjects, of whom 491 (25.0%) were grade I (30-34.9 kg/m2) and 314 (16.0%) were grade II/III (≥35 kg/m2).
in the multivariable adjustment model, the main outcome (i.e. IMV and/or death on the 7th day) and overweight (OR is 1.65 (1.05-2.59)), I-level (OR 1.93 (1.19-3.14)) and Type II/III obesity (OR 1.98 (1.11-3.52)).
after multivariative adjustment, the primary outcome on the 7th day was significantly associated with obesity in patients under 75 years of age, which was not present in patients over 75 years of age.
, overweight and obesity were associated with poor early prognostics in T2D patients hospitalized with COVID-19.
, the harmful effects of obesity on COVID-19 prognosmical conditions are no longer observed in older adults, highlighting the need to classify and manage this particular population.
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