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Recently, a research article was published in Diabetes, an authoritative journal in the field of diabetes , in which researchers used two-way Mendelian randomization (MR) to explore the relationship between blood sugar and cognitive function, brain structure, and dementia (AD).
diabetes
The data for this study comes from the British Biobank (n=500000).
Through IVW, researchers found that the genetic tendency of type 2 diabetes is related to RT (ß=1.
HbA1c has no correlation with RT (ß=1.
In general, there is little evidence that there is a causal relationship between genetic tools of T2D or peripheral blood glucose and indicators of middle-aged cognition and brain structure .
There is little evidence that there is a causal relationship between genetic tools of T2D or peripheral blood sugar and indicators of middle-aged cognition and brain structure
Original source:
Original source:Victoria Garfield,et al.
org/10.
2337/db20-0895" target="_blank" rel="noopener">The Relationship Between Glycaemia, Cognitive Function, Structural Brain Outcomes and Dementia: A Mendelian Randomisation Study in the UK Biobank in this message