Diabetogia: Preserved C-peptide secretion is associated with fewer low-sugar events and lower glucose variability and can be used to monitor rapid blood sugar in adults with type 1 diabetes.

The purpose !---- of this study was to assess whether the continuous secretion of C peptides in adults with type 1 diabetes was associated with less glucose variability and less hypoglycemia eventswe conducted a cross-sectional study of 290 people with type 1 diabetes who were treated at the diabetes clinic of the University Teaching Hospital, who used rapid monitoring and randomly obtained plasma c peptides over the past two yearsthe relatively low c peptide (-lt;10 pmol/l) individual seofs with the active cpeptide (10 - 200 pmol/l or 10 - 50 pmol/l) individual flash monitoring related variables, the relationship between self-reported hypoglycemia and c peptides was also assessed based on the median (quartile range) (n s 167)results show that, although there is no difference in the current age in this queue, c-peptide secretion (10-200 pmol/l) of individual diabetes disease shorter (15 s.24? vs 25 s.15 -34 years, p .lt; 0.001) and the diagnostic age is older (23 s.28?blood sugar s.lt;3.9 mmol / l (3% s2 - 6%) shorter retention of C peptides (5% s .3-9%), p-lt;0.001), less low blood sugar events per two weeks (7 s.4-10) and 10 s.5-16, p-lt-0.001), glucose S Lower D (3.8 (3.8 (3.4-4.2) vs 4.1 (3.5-4.7) mmol / l, p - 0.017) and low CV of glucose (38.0 .35.0-41.6) vs 41.8 (36.5-45.8), p.0.001)these differences were also found in patients with c peptide 10-50 pmol/l, and the correlation was not related to the duration of diabetes and the estimated glycifying hemoglobin in the logistic regression analysisPreserved c peptides are also associated with a lower self-reporting rate of asymptomatic hypoglycemia (8.0% vs 22.8%, in the past month, p - 0.028)results showed that Preserved C peptide secretion was associated with fewer low-sugar events and lower glucose variability and could be used for rapid monitoringthis suggests that individuals with retained C peptides are safer at reaching their high blood sugar targets.