Diabetogia: Relationship between moderate and high-intensity physical activity and the incidence of type 2 diabetes and subsequent mortality?

The study used data from nearly 30 years to examine the role of physical activity in the onset of diabetesThe first goal is to study the long-term link between moderate exercise and the incidence of type 2 diabetesThe second goal was to investigate the relationship between high-intensity physical activity after diabetes and the subsequent risk of all-out causes and cardiovascular disease deathsBased on clinical assessments conducted between 1985 and 2016 and electronic health records as of March 31, 2017, a total of 9,987 subjects from the type II cohort study (1985-1988) were followed up to investigate the incidence of type 2 diabetesWe first looked at the association between moderate and intense physical activity (average age 44.9 (SD 6.0 years) measured in questionnaires from 1985-1988 and the incidence of type 2 diabetes, using the interval-disease-death model, an analysis of the risk of intermittent competitive determination of diabetes, which takes into account the risk of death and the risk of diabetes due to dependence on data collection cycles (interval-death)The second analysis was based on individuals with type 2 diabetes during the follow-up period, and we used anti-probability weighted Cox regression to study the association between moderate to vigorous exercise after diagnosis of type 2 diabetes and the risk of death from cardiovascular diseasestudy showed that 1,553 of the 9,987 participants developed type 2 diabetes during an average of 27.1 (SD 6.3) years of follow-upParticipants who did moderate to high-intensity physical activity at any time had a lower risk of developing type 2 diabetes (HR 0.85 (95% CI 0.75, 0.97), p -0.02; analysis adjusted for sociodemographic, behavioral and health-related factors compared to participants who did not exercise from 1985 to 1988During the follow-up period, data on moderate to vigorous exercise after the diagnosis of diabetes were recorded in 1,026 participants diagnosed with type 2 diabetes, and 165 total cause and 55 cardiovascular-related deaths were recorded during the follow-up period of an average of 8.8 (SD 6.1) yearsIn these diabetes participants, the duration of any moderate to intense physical activity was associated with a lower overall mortality rate (HR 0.61 (95% CI 0.41, 0.93, phigh-intensity physical activity inhas an important effect on the occurrence and prognosis of diabetesWhen the duration of the activity is below the recommended value, the protective effect of morbidity can be observed, while the longer the duration of the activity, the additional benefits can be observedIn people with type 2 diabetes, any sustained moderate to high-intensity physical activity is associated with a reduction in all-cause mortality, and physical activity for the necessary time can prevent cardiovascular-related mortality