Diabetologia: esologic characteristics and prognostics of COVID-19 and diabetic hospitalized patients.

Coronavirus disease-2019 (COVID-19) is a deadly infection caused by the Severe Acute Respiratory Syndrome Coronary Virus-2 (SARS-CoV-2) virus.
diabetes has rapidly become a major co-disease of COVID-19 severity.
, the esolytic characteristics of diabetes in patients with COVID-19 are not yet known.
researchers conducted a national multi-center observational study of diabetics hospitalized with COVID-19 at 53 centres in France between March 10 and 31, 2020.
main results of joint tracheal intage mechanical breathing and/or death within 7 days of hospitalization.
the prognostic value of clinical and biological characteristics of endpoints using age- and gender-corrected multivariable logistic regression.
1 SD increase is reported as OR after standardization.
study included 1,317 participants, 64.9% male, with an average age of 69.8 to 13.0 years, with a median BMI of 28.4 (25-75%: 25.0-32.7) kg /m2;
46.8% and 40.8%, respectively, due to complications of microvascular and large vascular diabetes.
46.8% and 40.8% of microvascular and large vascular complications, respectively.
results were found in 29.0% (95% confidence interval 26.6, 31.5) of participants, 10.6% (9.0, 12.4) died, and 18.0% (16.0, 20.2) were discharged on the 7th day.
In a single-factor analysis, the characteristics significantly associated with the main results before hospitalization were sex, BMI, and the previous use of renin-angiotensin-aldosterone system (RAAS) blockers, regardless of age, type of diabetes, glycation of hemoglobin, complications of diabetes, or treatment of hypoglycemia.
in the pre-hospital multivariable covariance analysis, only BMI is still positively related to the main result (or 1.28 .
admitted to hospital, breathing difficulties (OR 2.10. 3.35), lymphocyte count (OR 0.67 (0.50, 0.88), c-reactive protein (OR 1.93 (1.43, 2.59)) and AST (OR 2.23(1.70, 2.93)) levels are the primary prognostic independent predictors.
, age (or 2.48 ( 1.74, 3.53) ), treated obstructive sleep apnea (or 2.80 ( 1.46, 5.38) ), microvascular Complications (or 2.14 (1.16, 3.94)) and complications of large blood vessels (or 2.54 (1.44, 4.50)) were independently associated with the risk of death on the 7th day.
in diabetics hospitalized for COVID-19, BMI was positively associated with tracheal ints and/or deaths within 7 days and was independent, but not related to long-term blood sugar control.
.