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A plant-based diet, especially one rich in healthy plant foods, is associated with a lower risk of type 2 diabetes
A plant-based diet, especially one rich in healthy plant foods, is associated with a lower risk of type 2 diabetes
We measured plasma metabolites in 10,684 participants using high-throughput LCMS in three prospective cohorts (the Nurses' Health Study, the Nurses' Health Study II, and the Health Professionals Follow-up Study)
We measured plasma metabolites in 10,684 participants using high-throughput LCMS in three prospective cohorts (the Nurses' Health Study, the Nurses' Health Study II, and the Health Professionals Follow-up Study)
Results A total of 55 metabolites of PDI, 93 metabolites of hPDI and 75 metabolites of uPDI were identified
Overall, metabolite profile scores for PDI (19% lower risk per 1 SD increase, HR = 0.
Reciprocal adjustment for a subset of selected metabolites in the metabolite profile, including triethylene glycol, hippocampal acid, isoleucine, and triacylglycerols, attenuated dietary indices PDI and hPDI associated with lower type 2 diabetes risk association
Reciprocal adjustment for a subset of selected metabolites in the metabolite profile, including triethylene glycol, hippocampal acid, isoleucine, and triacylglycerols, attenuated dietary indices PDI and hPDI associated with lower type 2 diabetes risk association
Taken together, plasma metabolites associated with a plant-based diet, especially a healthy plant-based diet, are associated with a lower risk of type 2 diabetes in the general healthy population
references:
references:Plasma metabolite profiles related to plant-based diets and the risk of type 2 diabetes.
Plasma metabolite profiles related to plant-based diets and the risk of type 2 diabetes.
Diabetologia (2022).
https://doi.
org/10.
1007/s00125-022-05692-8 Plasma metabolite profiles related to plant-based diets and the risk of type 2 diabetes.
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