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Purpose: Higher maternal body mass index during pregnancy is related to higher birth weight of offspring, but excessive birth weight is related to poor perinatal and neonatal outcomes
Higher maternal body mass index during pregnancy is related to higher birth weight of offspring, but excessive birth weight is related to poor perinatal and neonatal outcomes
Results: Maternal metabolism is good and obese is associated with lower birth weight of offspring (94[95% CI 150, 38]g[6.
Maternal metabolism is good and obese is associated with lower birth weight of offspring.
Table of the characteristics of the research used in the secondary analysis
Table of the characteristics of the research used in the secondary analysisFigure 1 Assessment of the causal effect of maternal metabolic obesity on the birth weight of offspring
Figure 1 Assessment of the causal effect of maternal metabolic obesity on the birth weight of offspring
Figure 2 Estimates of the causal effect of maternal body mass index on offspring's birth weight
Figure 2 Estimates of the causal effect of maternal body mass index on offspring's birth weight
Figure 3 Assessment of the causal effect of maternal BMI and well-metabolized obesity on maternal pregnancy blood glucose outcome
Figure 3 Assessment of the causal effect of maternal BMI and well-metabolized obesity on maternal pregnancy blood glucose outcome
Figure 4 The causal effect of maternal BMI and metabolically good obesity on other birth anthropometric results after adjustment according to the genotype of the offspring
Figure 4 The causal effect of maternal BMI and metabolically good obesity on other birth anthropometric results after adjustment according to the genotype of the offspring
Our results show that higher maternal obesity does not necessarily lead to higher birth weights in offspring
Thompson WD, Beaumont RN, Kuang A,et al.
Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile.
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