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    Home > Active Ingredient News > Endocrine System > Diabetologia: Obese mothers and good metabolic status can reduce the birth weight of offspring

    Diabetologia: Obese mothers and good metabolic status can reduce the birth weight of offspring

    • Last Update: 2021-12-03
    • Source: Internet
    • Author: User
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    Purpose: Higher maternal body mass index during pregnancy is related to higher birth weight of offspring, but excessive birth weight is related to poor perinatal and neonatal outcomes


    Higher maternal body mass index during pregnancy is related to higher birth weight of offspring, but excessive birth weight is related to poor perinatal and neonatal outcomes


    Results: Maternal metabolism is good and obese is associated with lower birth weight of offspring (94[95% CI 150, 38]g[6.


    Maternal metabolism is good and obese is associated with lower birth weight of offspring.


    Table of the characteristics of the research used in the secondary analysis

    Table of the characteristics of the research used in the secondary analysis

    Figure 1 Assessment of the causal effect of maternal metabolic obesity on the birth weight of offspring


    Figure 1 Assessment of the causal effect of maternal metabolic obesity on the birth weight of offspring


    Figure 2 Estimates of the causal effect of maternal body mass index on offspring's birth weight


    Figure 2 Estimates of the causal effect of maternal body mass index on offspring's birth weight


    Figure 3 Assessment of the causal effect of maternal BMI and well-metabolized obesity on maternal pregnancy blood glucose outcome


    Figure 3 Assessment of the causal effect of maternal BMI and well-metabolized obesity on maternal pregnancy blood glucose outcome


    Figure 4 The causal effect of maternal BMI and metabolically good obesity on other birth anthropometric results after adjustment according to the genotype of the offspring


    Figure 4 The causal effect of maternal BMI and metabolically good obesity on other birth anthropometric results after adjustment according to the genotype of the offspring


    Our results show that higher maternal obesity does not necessarily lead to higher birth weights in offspring


    Thompson WD, Beaumont RN, Kuang A,et al.


    Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile.


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