Diabetologia: The effect of insufficient sleep under standard dietary conditions on glycemic control disorders

Diet, physical activity and sleep are considered to be the core parts of a healthy life>
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Sleep disorders are often related to other diseases

Diet, physical activity and sleep are considered to be the core parts of a healthy life>

Methods: Data from healthy adults were analyzed from the PREDICT diet intervention trial (N=953[41% of twins])
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Researchers determined their metabolic response to different foods based on each participant's meal time, sleep time, and a series of biological characteristics.

Results: Sleep quality was significantly related to postprandial blood glucose control (2h increment AUC), both from person to person and at the individual level
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There is an interaction between sleep time and meal type.

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Figure 1 (A) Glucose 2h iAUC distribution by type of meal
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The box diagram shows the median and IQR; the whiskers represent IQR, and the outliers (>1.

Figure 1 (A) Glucose 2h iAUC distribution by type of meal

Figure 2 The effect of interaction between diet type and SPT on blood glucose 2h iAUC
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The graph uses the marginal effects of the interaction terms and standard errors to fit the model

Figure 2 The effect of interaction between diet type and SPT on blood glucose 2h iAUC

Table Blood glucose concentration at midpoint of sleep and after meal between people

Table Blood glucose concentration at midpoint of sleep and after meal between people

Conclusion: Low sleep efficiency and late going to bed habits are related to a higher postprandial blood glucose response after breakfast the next morning
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A person’s deviation from normal sleep patterns is also associated with poor postprandial blood sugar control

Low sleep efficiency and late bedtime habits are related to a higher postprandial blood glucose response after breakfast the next morning

Tsereteli N, Vallat R, Fernandez-Tajes J,et al.
Impact of insufficient sleep on dysregulated blood glucose control under standardised meal conditions.
Diabetologia 2021 Nov 30

Impact of insufficient sleep on dysregulated blood glucose control under standardised meal conditions.
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