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Dichlorophen
[Alias] 2,2'-Dihydroxy-5,5'dichlorophenylmethane
[Structural formula]
[Physical and chemical properties]
White crystals
[Preparation]
(1) Using sulfuric acid as a catalyst
The German Faben Company announced in 1927 a method for producing dichlorophenol, which is prepared by the condensation of p-chlorophenol and formaldehyde under the action of sulfuric acid or zinc chloride
The currently used method is to use sulfuric acid to react formaldehyde and p-chlorophenol in an alcohol solution at approximately 0°C
In the reaction kettle, first dissolve 405kg of 96% sulfuric acid in 300kg of water, pass in N 2 , maintain the temperature at 50-55 °C, and then cover
(2) Using molecular sieve as catalyst
In the early 1980s, Chen Zitao of Nanjing University proposed a process for preparing dichlorophenol using Y-type molecular sieve as a catalyst.
In a three-necked flask, put 63.
[application]
(1) Circulating cooling water treatment
Dichlorophen is used as a bactericidal and algaecide, and has a strong killing and inhibitory effect on heterotrophic bacteria, iron bacteria, sulfate reducing bacteria, cyanobacteria and green algae in circulating cooling water
(2) Medical applications
Diclofenac sodium can be used as an anti-inflammatory drug.