Diet in Vitamin A Research
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Last Update: 2020-12-29
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Source: Internet
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Author: User
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A properly formulated diet is an essential underpinning for all in vivo research. This chapter focuses on the use of dietin retinoid research from two perspectives: human research, in which diet is usually variable and analysis of dietary intakeis paramount to interpreting the study’s results, and animal (rodent) research, in which diet is imposed as a factor in theexperimental design, and the diet consumed is usually monotonous. Many standard rodent diets are nonpurified and the amountof vitamin A in the diet is unknown. Moreover, it is likely to be much higher than expected from the label. By using a well-formulatedpurified diet with an exact amount of vitamin A, retinoid status in rodents can be closely controlled to create specific physiologicalconditions that represent the wide range of vitamin A status present in human populations.
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