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Pancreatic cysts are common, with an estimated prevalence of 2-15% worldwide, and with the increased use of CT cross-sectional imaging, physicians are finding more cases in patients without other signs or symptoms of pancreatic disease Occasional pancreatic cyst
.
Once detected, these cysts can trigger severe anxiety in patients about pancreatic cancer development and death
Examples include pseudocysts and serous cystadenomas, as well as potentially malignant cysts such as intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs)
Pancreatic cancer incidence in patients with pancreatic cysts was calculated during long-term follow-up using a large national cohort
We conducted a retrospective cohort study of U.
S.
veterans diagnosed with pancreatic cysts from 1999-2013 according to International Classification of Diseases 9th Edition (ICD9) codes from the U.
S.
Department of Veterans Affairs (VA) data
.
Pancreatic cancer incidence was determined using VA Cancer Registry data, ICD-9 codes, and the National Mortality Database
RESULTS: Among 7,211 veterans with pancreatic cysts, 79 (1.
1%) developed pancreatic cancer during a total of 31,501 person-years of follow-up (median follow-up 4.
4 years)
.
A total of 1982 patients (27.
Disease changes in pancreatic cysts over time
Disease changes in pancreatic cysts over time
This study demonstrated very low pancreatic cancer incidence and pancreatic cancer-related mortality in a large cohort of patients with VA pancreatic cysts with long-term follow-up
.
Most deaths were from non-pancreatic cancer and cardiovascular causes, with only a minority (3.
In a large cohort of patients with VA pancreatic cysts with long-term follow-up, pancreatic cancer incidence and pancreatic cancer-related mortality were very low
Original source:
Original source:Gobind S.
Gobind S.
Anand.
Et al.
Pancreas Cancer Incidence and Pancreas Cancer-Associated Mortality Are Low in National Cohort of 7211 Pancreas Cyst Patients.
Digestive Diseases and Sciences.
2022.
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