Dig Dis Sci: The thickness of the vein wall may be a unique diagnostic tool for distinguishing between behelodent and intraintestinal infections and Crohn's disease.

BD is a systemic inflammatory disease characterized by oral and genital ulcers, other manifestations and systemic suffering including major blood vessels, musculoskeletal, nervous system and gastrointestinal (GI) systems.
gastrointestinal system (GI) sufferer in
BD usually manifests it as abdominal pain, followed by diarrhea, bleeding, vomiting, changes in bowel habits, weight loss, fistula and perforation, all of which can also occur frequently in inflammatory bowel disease.
BD and CD also have some genetic background and immunopathological similarities, such as the IL-17/23 pathway.
the two diseases are difficult to distinguish among young people with nonse specific gastrointestinal manifestations due to similar intestinal manifestations.
recent study found that the increase in the thickness of the total vein (CFV) is a significant feature of BD, rarely seen in other inflammatory or vascular diseases alone, and that for ≥0.5 mm of CFV thickness, the diagnosis of BD specificity is higher than 80%.
, this study evaluates the diagnostic performance of CFV thickness diagnostics in BD and CD identification diagnostics.
researchers collected several patients from each of the patients with BD (n s 69), CD (n s 38) and health control (HC) (n s 38).
the thickness of the bilateral CFV with a Doppler ultrasound, and then used the ROC curve to determine the effectiveness of CFV in diagnosing disease accuracy.
the left and right CFV thicknesses of BDs are significantly higher than those of HCs and CDs (right: 0.76 mm VS 0.33 mm, left: 0.78 mm VS 0.35 mm, both p-lt;0.001).
the CFV thickness in the CD is similar to that of the HC (both p.gt; 0.05).
CFV thickness was similar in patients with and without gastrointestinal burdens (p s 0.367).
truncation value of the CFV thickness is ≥0.5 mm, which is a good distinction between CD and HC.
positive and negative predictive values of 90%.
researchers concluded: CD CFV thickness is much lower than BD, CFV wall thickness measurement may be a unique diagnostic tool to distinguish between BD and CD, can help distinguish between the two diseases in daily practice.
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