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Do you know about these adverse reactions and contraindications of prokinetic drugs?

 Last Update: 2021-04-19
 Source: Internet
 Author: User

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Author: Li Junchen This article is the author's permission NMT Medical publish, please do not reprint without authorization.

In clinical work, gastroenterologists often encounter patients with gastrointestinal dysmotility symptoms such as nausea, abdominal distension, early satiety, belching, and constipation.
Therefore, they need to prescribe corresponding gastrodynamic drug treatments according to the actual situation to improve patients' discomfort symptoms.

Do you know the adverse reactions and contraindications of commonly used gastrokinetic drugs? The mechanism of action and safety of various gastrointestinal motility drugs are shown in Table 1, as follows: Table 1 Comparison of the mechanism of action and safety of various gastrointestinal motility drugs (click to view larger image) Gastrointestinal motility drugs can enhance the stomach Intestinal smooth muscle contraction, coordinate gastrointestinal peristalsis, promote gastrointestinal emptying, reduce visceral hypersensitivity, antiemetic and other mechanisms to improve the above symptoms of patients.

Many doctors in clinic have used this kind of drugs, but if the clinician grasps it well, it is a good medicine, if it is not grasped well, it is a deadly poison.

Do you know the indications for the use of various gastrointestinal motility drugs, especially the adverse reactions and contraindications? Table 2 Indications, adverse reactions and contraindications of various gastrointestinal motility drugs (click to view larger image) Reference source: 1.
Zhou Qi, Jiang Zheng.
Trimebutine maleate combined with mosapride on the function The influence of gastric hormone levels in patients with dyspepsia[J].
Journal of Clinical Drug Therapy 2019; 17(9): 61-642.
Gastrointestinal Dynamics Group, Chinese Medical Association Gastroenterology Branch.
Guidelines for the diagnosis and treatment of dyspepsia in China (2007 Dalian) [J].
Gastroenterology 2008; 13(2): 114-1173.
Chinese Medical Association Geriatrics Branch.
Expert consensus on diagnosis and treatment of functional dyspepsia in the elderly[J].
Chinese Journal of Geriatric Research 2015; 2(3) : 1-74.
Feng Zhiwen.
Study on the success rate of erythromycin combined with metoclopramide on naso-intestinal tube placement with bare hands[J].
Electronic Journal of Clinical Medicine 2019; 6(63): 1675.
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Plukka Comparison of the effects of Bili and Itopride in bowel preparation in patients with chronic constipation[J].
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Different gastrointestinal motility drugs in capsule endoscopy Comparative study in Chinese[J].
Chinese Journal of Physician Training 2016; 39(5): 425-4287.
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