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Biotechnology Channel News: Probiotics are a class of microorganisms that help the health of the human body, which can reproduce in the body's intestines and reproductive system, and can produce exact health effects to improve the micro-ecological balance of the host body.
Recently, researchers from the University of Otago found that a home-grown probiotic may reduce a woman's risk of gestational diabetes, while also lowering an individual's blood sugar levels on an empty stomach, and that researchers have found that probiotics may be effective in treating diseases such as allergies.
discovery of probiotics or improved cognitive function in the brains of Alzheimer's patients! In a study published in the international journal Frontiers in Aging Neuroscience, researchers from Islamic asad University and other institutions found for the first time that probiotics improve cognitive function in the human brain. In the 2-week study, a single daily dose of lactic acid bacteria and Bipolibab bacteria may significantly improve scoring in elderly Alzheimer's patients with MMSE, a standard test for cognitive impairment.
Probiotics can help protect the body against specific infectious diarrhea, irritation syndrome, inflammatory bowel disease and other diseases, and researchers have long assumed that probiotics may enhance cognitive function in the brain because there is a two-way communication between the gut, gastrointestinal tract and brain In mice, probiotics improve their ability to learn and remember, while reducing anxiety and depression in mice, but researchers have not found in previous studies that probiotics improve cognitive function in the human brain.
Genetically modified probiotics prevent bacterial infection of probiotics, originally derived from the Greek word for "life-good", refers to active microorganisms that improve the micro-ecological balance in the intestines of hosts (e.g. animals or humans) and have positive benefits for hosts.
A genetically modified probiotic can prevent and eliminate bacterial infections in animal models, demonstrating the potential of pathogens to be "pre-empirical," according to a study of microbiology published online Monday in the British journal Nature Communications.
genetically modified bacteria can be used to kill specific pathogens.
previously, researchers had modified a laboratory strain of E. coli to crack when the pathogen green pus was present around it and release a toxin that selectively kills the pathogen.
, however, it has not been clear whether this method can be used to prevent bacterial infections in animals.
This time, Matthew Zhang, a researcher at Singapore International University, and colleagues "reinvented" E. coli Nissle 1917, a probiotic that has been shown to be beneficial for certain intestinal diseases and is thought to be effective and safe in treating and relieving ulcerative colitis, false membrane gastroenteritis and acute and chronic enteritis.
experiments, the modified E. coli Nissle 1917 was added to new features, including a gene that allows it to disrupt the stability of the biofilm of E. coli.
biofilm is a surface attachment aggregate that is difficult to decompose. The
team successfully tested the effectiveness of retrofitting probiotics in two animal models of intestinal infections (mice and beautiful cryptobacteria) and found that it was more effective in preventing outbreaks of infection than in fighting existing infections.
team noted that the newly genetically modified probiotics now have the benefits associated with conventional probiotics, as well as the potential to prevent infection of certain pathogens.
further research is needed to test whether these findings can be applied to humans.
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