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    Home > Active Ingredient News > Endocrine System > Does diabetes go away on its own?

    Does diabetes go away on its own?

    • Last Update: 2022-04-29
    • Source: Internet
    • Author: User
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    *For medical professionals to read and reference diabetes "remission" needs to be vigilant! Diabetes is a lifelong disease.
    Generally, only a small number of patients with mild type 2 diabetes can achieve “clinical remission” through early “intensive insulin therapy”, that is, patients do not need insulin injections or hypoglycemic drugs, and rely solely on diet control and exercise.
    Normal blood sugar can be maintained
    .

    "Cure diabetes" is the common wish of all diabetic patients, but with the current level of science and technology and medical status, it cannot be achieved for the time being.
    However, in real life, sometimes there are such "good things" that fall out of the sky.
    Take a look at the following example: A clinical example Teacher Zhang was diagnosed with diabetes shortly after retiring from school.
    From then to now, she has lived like an ascetic for more than ten years, strictly controlling her diet and exercising, rain or shine, twice a day.
    Insulin injection
    .

    Although Mr.
    Zhang's blood sugar has been well controlled over the years, he knows the joys and sorrows
    .

    Teacher Zhang often pours bitterness to the neighbors: "If you can cure diabetes, you can no longer take injections and medicines every day, you can eat as much as you want, and you don't have to worry about blood sugar rising, that would be great!" It will be realized soon! After the Spring Festival this year, she often felt flustered, sweated, and felt hungry, and her blood sugar was low on many self-tests.
    Teacher Zhang simply stopped her insulin on her own initiative, and her blood sugar was not high even in the re-examination
    .

    The diabetes that has plagued Mr.
    Zhang for many years is finally "recovered".
    It stands to reason that Mr.
    Zhang should be happy, but on the contrary, Mr.
    Zhang, who has always been neat and quick-talking, seems to have changed a person, and is listless and taciturn all day long.
    , I don't want to eat, I'm tired and lethargic, and I'm extraordinarily afraid of the cold.
    I'm still wearing thick cotton-padded clothes at home in March, and my face is also a little swollen and sallow
    .

    Two days ago, her family took her to the hospital for examination.
    Although her blood sugar was not high, her blood pressure and blood sodium were significantly lower than normal, and the hormone levels of the three axes (pituitary-adrenal axis, pituitary-thyroid axis, and pituitary-gonadal axis) were generally reduced.
    , Brain magnetic resonance imaging (MRI) found pituitary infarction, and the final diagnosis was "Houssay syndrome"
    .

    Glucocorticoids (cortisone) and thyroid hormone replacement therapy were given for treatment.
    After 2 to 3 weeks, Mr.
    Zhang's symptoms such as chills, anorexia, and drowsiness were significantly improved, and his face was not swollen
    .

    But at the same time, her blood sugar gradually started to rise again, so she restarted insulin treatment, and now her blood sugar is well controlled and everything is back to normal
    .

    What is this "strange" Housay syndrome? Seeing this, many patients may have to ask, what kind of disease is "Housay syndrome"? Why does this disease make the blood sugar of diabetic patients return to normal on their own? It all starts with the function of the pituitary gland
    .

    We know that the pituitary gland (including the adenohypophysis and the neurohypophysis) is an important central endocrine organ in the human body.
    When the adenohypophysis develops pathological changes for some reasons, it secretes various secretory hormones (such as adrenocorticotropic hormone, adrenocorticotropic hormone, Thyroid-stimulating hormone, gonadotropin, etc.
    ) and target glands (such as adrenal glands, thyroid, gonads, etc.
    ) regulated by secretagogue hormones (such as adrenal cortex hormones, thyroid hormones, sex hormones, etc.
    ) are reduced, and these hormones belong to Insulin antagonist hormones (or "glucose hormones"), which have the effect of raising blood sugar
    .

    Therefore, when the secretion of these insulin antagonistic hormones is reduced, it will cause the patient's blood sugar to drop and the symptoms of "three more and one less" diabetes to disappear
    .

    "Houssay syndrome", also known as "diabetic spontaneous remission syndrome", refers to a metabolic abnormal syndrome caused by diabetes combined with anterior pituitary hypofunction
    .

    The reason why Mr.
    Zhang's diabetes self-healed in the article is because of pituitary infarction caused by diabetic microvascular disease, leading to hypofunction of the anterior pituitary gland and insufficient secretion of blood glucose-raising hormones (such as adrenal cortex hormone, thyroid hormone, growth hormone, etc.
    ).
    Normal blood sugar is not a good thing, but the result of one disease overshadowing another
    .

    "Houssay syndrome" is not difficult to diagnose, through detailed medical history (diabetes remission or even hypoglycemia) + physical examination (apathy, thinning hair, dry skin, etc.
    ) + laboratory examination (electrolyte imbalance (such as low sodium), pituitary gland And target gland (adrenal gland, thyroid, gonad) hormone levels decreased] + pituitary MRI, etc.
    , can be diagnosed
    .

    Therefore, diabetes "self-healing" may not be a good thing, it is likely to be "pituitary apoplexy" or "hypophysitis"
    .

    Once such a situation is encountered clinically, it is necessary to go to the hospital for further investigation as soon as possible, so as not to mistake a bad thing for a good thing and delay the diagnosis and treatment of the primary disease
    .

    And diabetic patients also need to remember that "remission" of diabetes ≠ "cure", if the patient relaxes self-management, hyperglycemia will still come back! References: [1] Wang Jianhua.
    Diabetes Self-Management Lecture Hall [M].
    Beijing: China Science and Technology Press, 2017: 58-59.
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