Does life on a sterile spaceship destroy the healthy microbiome in animals?

According to foreign media reports, NASA sent 10 mice to the International Space Station, using 90 days of observational experiments and compared with 10 mice living on Earth to understand how animals change in the body's microbiome in the space environment.
living in space can your gut bacteria disorder? Twenty mice are about to reveal the answer to this question.
early Friday morning, SpaceX launched its 15th resupply mission from Cape Canaveral, carrying the nearly 6,000-pound Dragon spacecraft into orbit.
most of the payloads are scientific instruments and equipment to help the six astronauts on the space station conduct scientific research.
one of the experiments will include punctures, weighing and analysis of fecal composition on the International Space Station and 20 mice on Earth, as well as real-time observations of the mice while they sleep.
the study aims to determine how life in a sterile spaceship in space alters the circadian rhythm of an animal and destroys the animal's healthy microbiome.
the rodents were part of the study because before NASA began sending humans to Mars, they wanted to know how long journeys could disrupt bodily functions, including how all parasitic bacteria in the body would react.
10 of them will spend 90 days in space (about nine years in modern human sons). "I'm trying to understand the chain of events that occur when microgravity interferes with sleep and wake-up cycles," said Martha Vitaterna,
deputy director of the Center for Sleep and Circadian Physiology At Northwestern University and one of the research leaders.
" microbes produce basic molecules that humans and mice cannot produce, and Vitatner and her colleagues wanted to know whether these changes in chemical signals affect the host's ability to fight problems such as sleep loss, which can disrupt the body's metabolism and immune system.
her team sent two different mice into space, one that snoozed normally in zero-gravity conditions and the other that slept lightly in a simulation.
mice with poor sleep quality were not able to produce melatonin because of genetic factors.
the two species of mice will be housed in a NASA research facility, home to the same habitat as on the International Space Station -- a sealed metal box with air-locked windows and a pollen air filtration system.
they will be placed in exactly the same environment, with gas composition, temperature, simulated day and night lights, and all the same.
but the ground-ground environment is three days slower than the International Space Station.
the environmental data stream stored at the International Space Station will tell scientists on the ground how to replicate the station's lab every minute.
the project is similar to NASA's Space Year study, in which astronaut Scott Kelly made 340 days of intensive observations on the International Space Station, and his identical twin brother, Mark, a retired NASA astronaut, went through the same steps on Earth.
Northwestern University was one of 10 research groups from across the country who joined forces to study how space changed Scott's body.
Vitaturner's team found that zero-gravity life changed the balance between the two main bacteria in Scott Kelly's gastrointestinal tract, but when he returned to Earth, everything returned to normal.
spacecraft must remain extremely clean to protect astronauts from dangerous pathogens, and scientists have been wondering whether the lack of bacteria will make it difficult to replenish the diversity of communities.
but overall, scientists were surprised that the overall diversity of gut microbes in his year in space changed so little.
: NASA astronaut Barry " Barry "Butch" Wilmore installs the rodent Reseach1 experimental hardware at the International Space Station through a microgravity science glove box.
to continue to learn this further, NASA is currently conducting a larger study, the Astronaut Microbiome Project, to track the bacterial communities of astronauts before, during and after missions.
as early as 2013, NASA began collecting astronauts' blood, saliva and swabs (from the forehead, armpits, yes, and buttocks) and conducted a final round of collections in February.
the results will provide the best observation to date about how space affects human bacteria, including on the body's metabolism and immune function.
you can observe astronauts, but you can't dissect them directly.
not for rodents in the experiment.
after this trip, scientists will study different organs, such as the liver and spleen, to better understand any link between inflammation, metabolic changes and changes in the microbiome.
all this information is critical to designing a Mars mission and keeping astronauts functional.
If all goes according to plan, the mice will arrive at the space station on Monday, July 2, along with a grinning companion robot and a special miniature aquarium, which is actually a microchemical park that grows in zero gravity.
more scientific research to launch on the International Space Station.
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