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EClinicalMed: Correlation between the characteristics of intestinal flora and the clinical prognosis of community-acquired pneumonia

 Last Update: 2021-08-27
 Source: Internet
 Author: User

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The interaction of the intestinal flora with the immune system may help prevent community-acquired pneumonia (CAP)

Immunization prevention

The purpose of this exploratory study is to characterize the composition of the rectal flora and virus during the hospitalization of CAP patients, and to determine whether the microbiota characteristics are related to clinical prognosis

Researchers conducted a prospective observational cohort study of CAP patients and control groups admitted to Dutch universities or community hospitals from October 2016 to July 2018

Differences in the abundance of intestinal flora between CAP patients and control individuals

A total of 64 patients and 38 controls were included

Rectal bacteria of CAP patients α Diversity of rectal bacteria α and β and β diversity of CAP patients are different from those of the control group.

Correlation between the characteristics of bacterial and viral microbiota and the clinical prognosis of CAP patients

In summary, this exploratory study provides preliminary evidence that the characteristics of the intestinal flora and virus group may be related to the clinical prognosis of patients with CAP

It showed that the intestinal flora and virus group features may be associated with clinical prognosis of patients with CAP intestinal flora and virus characteristics indicate that the group may be related to the clinical outcome of patients with CAP diagnosis

Original source:

Robert FJKullberg, et al.

Rectal bacteriome and virome signatures and clinical outcomes in community-acquired pneumonia: An exploratory study

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