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    Home > Active Ingredient News > Antitumor Therapy > Effect of uterine approidation on tumor prognosis in endometrial cancer patients: a retrospective study from 15 gynaecological oncology centers in Spain

    Effect of uterine approidation on tumor prognosis in endometrial cancer patients: a retrospective study from 15 gynaecological oncology centers in Spain

    • Last Update: 2021-01-30
    • Source: Internet
    • Author: User
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    AJOG Published: July 18, 2020 DOI: Https://doi.org/10.1016/j.ajog.2020.07.025 Focus 1. Endometrial cancer confined to the uterus using laparoscopic surgery, the use of uterine approidation for endometrial cancer prognosis is even worse.
    2. The uterine device may damage lesions confined to the uterus by increasing uterine pressure, worsening the tumor prognosis.
    3. This can be explained by macro (muscle layer rupture) and micro (tumor microencienties) assumptions.
    . The application of utour in tumor surgery should be reconsidered.
    background so far, the available evidence is not clear whether the use of laparoscopic surgery on endometrial cancer will affect the prognosis of the tumor.
    available evidence comes from retrospective studies of small samples.
    there is not enough evidence to support the use of the utive device, the surgical doctor must be based on personal choice and surgical experience to decide whether to use the utive device.
    study evaluated the role of urinals in the surgical treatment of laparoscopic surgery for early endometrial cancer and assessed tumor outcomes.
    designed this study as a retrospective multi-center study to evaluate the safety of uterine devices for early endometrial cancer patients.
    the type of uterus, surgical stage, tissue pathology, lymphatic vasovascular tube gap violation, FIGO stage, auxiliary treatment, recurrence, recurrence type, etc. were evaluated.
    main purpose of the study is to determine the recurrence rate.
    secondary purpose is to determine the recurrence rate, the total survival rate, and the recurrence pattern.
    results included 2,661 patients from 15 cancer centers, of whom 1,756 had hysterectomy using a uterine organ and 905 had laparoscopic surgery without using a uterine organ.
    two groups maintained a balance in tissue pathology, tumor grading, muscle layer immersion, FIGO phased, auxiliary therapy, etc.
    the recurrence rate of the urinal group was 11.69%, and the recurrence rate of the non-lifter group was 7.4%.
    the use of the lifter was accompanied by a higher recurrence rate (risk ratio 2.31; 95% CI, 1.27 to 4.20; p-0.006).
    application of uterine uterine approidator in patients with endometrial cancer (FIGOI-II) confined to the uterus with a lower disease-free survival rate (risk ratio 1.74; 95% CI, 0.57 to 0.9) 7;n=0.027) is associated with a higher risk of death (risk ratio 1.74; 95% CI, 1.07 to 2.83; p=n 0.026).
    there was no significant difference between the two sets of recurrence patterns (χ2 s 1.74; p s 0.63).
    the patients in this study underwent laparoscopic surgery, and the use of uterine uterine devices was associated with adverse prognostic outcomes of tumors in patients with endometrial cancer (FIGOI-II) that was confined to the uterus.
    conclusions of this study have yet to be confirmed by further prospective tests.
    Zhang Shi former source: Zhang Shi former public number copyright notice: All the text, pictures and audio and video materials marked "Source: Mets Medicine" or "Source: MedSci Original" are owned by Mace Medical, without authorization, no media, website or individual may reproduce, authorized to reproduce must indicate "Source: Mets Medicine".
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