Elevated stress hormones are linked to increased risk of high blood pressure and heart disease

Dallas, September 13, 2021 - Adults with normal blood pressure and high levels of stress hormones are more likely to develop high blood pressure than people who experience cardiovascular disease and low levels of stress hormones, according to new research published in Hypertension , Journal of the American Heart Association

Studies have shown that long-term exposure to daily stressors and traumatic stress can increase the risk of cardiovascular disease

"The stress hormones norepinephrine, epinephrine, dopamine and cortisol will increase with the stress of life events, work, relationships, finances, etc.

"Previous studies have focused on the relationship between stress hormone levels and cardiovascular events in patients with hypertension or hypertension

The subjects of the study are part of the MESA Stress 1 study, which is a sub-study of the Multi-Ethnic Study of Atherosclerosis (MESA).

The researchers followed the participants three times (September 2005 to June 2018) to find out if they had high blood pressure and cardiovascular diseases, such as chest pain, whether they needed to open their arteries, heart attacks, or strokes

Norepinephrine, epinephrine and dopamine are catecholamine molecules that can maintain the stability of the entire autonomic nervous system

Inoue said: "Although all these hormones are produced in the adrenal glands, they have different effects and mechanisms in affecting the cardiovascular system, so it is important to study their relationship with hypertension and cardiovascular events separately

Their analysis of the relationship between stress hormones and the development of atherosclerosis found:

• During an average follow-up of 6.

  
  

• During an average follow-up of 11.

  
  

"Researching psychological stress is challenging because it is personal and its impact varies from person to person

"The next key research question is whether increased stress hormone testing is helpful and for whom

One limitation of this study is that it did not include people with high blood pressure at the beginning of the study, which would lead to a larger study population

Co-authors Tamara Horwich, MD; Roshni Bo, MD; Karan Bhatt; Tina Goldwater, MD, Ph.

This research was funded by the National Heart, Lung, and Blood Institute of the National Institutes of Health, the Barbra Streisand Women’s Health Project at UCLA, the National Institutes of Health, the Tovler Prize at UCLA, and the Benjo International Foundation.

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