Elevated transaminases = impaired liver function?

Transaminases are a class of enzymes that catalyze the transfer of amino groups between amino acids and keto acids
.

It is commonly found in the cardiac muscle, brain, liver, kidney and other animal tissues

Transaminases are a class of enzymes that catalyze the transfer of amino groups between amino acids and keto acids

ALT catalyzes the transamination between glutamate and pyruvate, and AST catalyzes the transamination between glutamate and oxaloacetate

AST has the greatest activity in the heart, followed by the liver; ALT has the greatest activity in the liver.

Determination of transaminase activity in blood can be used as a diagnostic indicator in clinical practice

Elevated transaminases do not necessarily mean liver damage! Elevated transaminases do not necessarily mean liver damage!

When liver cells are damaged by inflammation, necrosis, poisoning, etc.

, transaminase will be released into the blood, which will increase serum transaminase

When liver cells are damaged by inflammation, necrosis, poisoning, etc.

1 % liver cell damage can double the concentration of ALT in the blood .

Therefore, ALT levels can be more sensitively monitored for liver damage

High transaminases are not necessarily all hepatitis

There are 7 reasons for elevated transaminases ! There are 7 reasons for elevated transaminases !

Diseases of the liver itself: especially various types of viral hepatitis, cirrhosis, liver abscess, liver tuberculosis, liver cancer, fatty liver, hepatolenticular degeneration, etc.

, can cause varying degrees of elevated transaminases

Diseases of the liver itself: especially various types of viral hepatitis, cirrhosis, liver abscess, liver tuberculosis, liver cancer, fatty liver, hepatolenticular degeneration, etc.

Diseases of other organs: In addition to the liver, other organs and tissues in the body also contain this enzyme

Biliary duct and pancreas disease: Because transaminase is excreted from the bile duct, if there is bile duct, gallbladder and pancreas disease, bile duct obstruction can also increase transaminase
.
Cholangiopancreatic diseases:

Drug-induced or toxic liver damage: Drug allergy can cause elevated transaminases, often accompanied by cholestatic jaundice and hepatocellular damage
.
Take medicines that can damage the liver when you are sick, such as erythromycin, tetracycline, sleeping pills, antipyretic analgesics, contraceptives, as well as Chinese herbs such as Pinellia, betel nut, and indigo
.
Transaminases levels return to normal quickly after stopping these drugs
.

Drug-induced or toxic liver damage: Drug allergy can cause elevated transaminases, often accompanied by cholestatic jaundice and hepatocellular damage
.
Take medicines that can damage the liver when you are sick, such as erythromycin, tetracycline, sleeping pills, antipyretic analgesics, contraceptives, as well as Chinese herbs such as Pinellia, betel nut, and indigo
.
Transaminases levels return to normal quickly after stopping these drugs
.
Drug-induced or toxic liver damage:

Pregnancy: normal pregnancy, pregnancy toxicity, acute fatty liver of pregnancy, etc.
are also common causes of elevated transaminases
.

Pregnancy: normal pregnancy, pregnancy toxicity, acute fatty liver of pregnancy, etc.
are also common causes of elevated transaminases
.
Pregnancy:

Bad living habits: long-term alcoholism leads to alcoholic liver, or unreasonable diet structure leads to fatty liver, resulting in elevated transaminases
.

Bad living habits: long-term alcoholism leads to alcoholic liver, or unreasonable diet structure leads to fatty liver, resulting in elevated transaminases
.
Bad habits:

Other conditions: Transaminase levels in healthy individuals may also temporarily exceed normal ranges
.
Strenuous exercise, over exertion, or having recently eaten greasy food may all temporarily increase transaminases
.
If you work overtime the night before the transaminase test, don't sleep well, or eat fried food for breakfast before the test, the test results may be outside the normal range
.
A person who has just run a few laps in the playground and immediately checks his aminotransferase level may also get higher than normal
.

Other conditions: Transaminase levels in healthy individuals may also temporarily exceed normal ranges
.
Strenuous exercise, over exertion, or having recently eaten greasy food may all temporarily increase transaminases
.
If you work overtime the night before the transaminase test, don't sleep well, or eat fried food for breakfast before the test, the test results may be outside the normal range
.
A person who has just run a few laps in the playground and immediately checks his aminotransferase level may also get higher than normal
.
Other cases: leave a message here