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    Home > Biochemistry News > Biotechnology News > Enantioseparations by Capillary Electrophoresis Using Cyclodextrins as Chiral Selectors

    Enantioseparations by Capillary Electrophoresis Using Cyclodextrins as Chiral Selectors

    • Last Update: 2020-11-27
    • Source: Internet
    • Author: User
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    Due to their commercial availability, cyclodextrins are the most frequently used chiral selectors in capillary electrophoresis as documented by the numerous publications in the field. A variety of migration modes can be realized depending on the characteristics of the cyclodextrins and the analytes. The basic considerations regarding the development of a chiral CE method employing cyclodextrins as chiral selectors are briefly discussed. The presented examples illustrate the separation modes of an acidic and a basic analyte with native and charged cyclodextrin derivatives as a function of the pH of the background electrolyte and the cyclodextrin concentration.
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