Endoscopy: The role of clotting enzymes and cyanide injections in controlling acute gastric varicose bleeding

Acute gastric curvy bleeding (AGVH) is a serious complication of hyperbaric hypertensionEndoscopic cyanide injection sinoxalate is a standard treatment for acute hemostatic, however, it may be associated with serious complicationsThe effect of clotting enzyme injectionhashashashast has not been confirmedThis study compared the role of injecting clotting enzymes and glues in AGVH hemorrhage68 eligible AGVH patients were randomly injected with coagulase (33) or glue injections (35)The main endpoint is injection-induced stomach ulcersSecondary endpoints are acute hemorrhage, rebleeding and 42-day mortalityresults show that the two sets of baseline data are comparableThe hemostatic rate of active bleeding during endoscopy was 90.0% (9/10), the glue group was 90.9% (10/11) (P-0.58), and the 48-hour hemorrhage rate was 93.9% (31/33) and 97.1% (34/35) (P.60)Treatment failed at 5 days in 2 patients (6.1%) and 2 patients in the glue group (5.7%) at 5 days (P.99)No gastric ulcer seismorated in the clotting enzyme group occurred in 11/30 (36.7%) of the group (P 0.001, 95% confidence interval (CI) 8% - 27%)4 (12.1%) and 18 (51.4%), respectively( complications in the clotting enzyme group and 18 (51.4%) (P .001,95 % CI 22 % - 45%, respectively)Two patients who received glue developed stomach ulcer bleeding after treatmentOne patient died in each group, the results show that injection of coagulation enzyme stoave under the endoscopic is similar to injection glue in achieving a successful AGVH nodingHowever, the incidence of complications of injection of glue is high