ESMO Open: Health-related quality of life helps predict the short-term mortality risk of patients with ovarian cancer!

Recurrent ovarian cancer (rOC) is an incurable disease with a poor prognosis.

Ovarian cancer

Health-related quality of life (HRQoL) is a self-reported prognostic indicator of patients, usually used to measure the effect of treatment, and is an independent predictor of patient survival.

Health-related quality of life (HRQoL) is a self-reported prognostic indicator of patients, usually used to measure the effect of treatment, and is an independent predictor of patient survival.

974 patients from 3 clinical studies from NOGGO were included in the exploratory analysis cohort, and 1,235 patients from multiple clinical studies from AGO were included in the validation cohort.

Short-term mortality of patients in different risk groups

Short-term mortality of patients in different risk groups

The receiver operating characteristics analysis shows that the area under the curve in the exploratory analysis and verification analysis of Model 1 are 0.

The area under the curve in the exploratory analysis and validation analysis of Model 1 were 0.

Death risk prediction performance

Death risk prediction performance

In summary, the risk scoring method developed in this study that incorporates HRQoL can well distinguish patients with recurrent ovarian cancer with low, medium, and high short-term mortality.

The risk scoring method developed in this study that incorporates HRQoL can well distinguish patients with recurrent ovarian cancer with low, medium, and high short-term mortality.

Original source:

Armbrust R,Richter R,Woopen H et al.

org/10.
1016/j.
esmoop.
2021.
100081" target="_blank" rel="noopener">Impact of health-related quality of life (HRQoL) on short-term mortality in patients with recurrent ovarian, fallopian or peritoneal carcinoma (the NOGGO-AGO QoL Prognosis-Score-Study): results of a meta-analysis in 2209 patients

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