Eur Heart J: The incidence of thoracic-abdominal aortic aneurysms in HIV-infected patients has increased by 4 times!

The introduction of combined antiretroviral therapy has greatly improved the HIV infection prognosis person (PLWH), but long-term survival of HIV-infected persons is still below the uninfected person, in part because HIV-infected patients heart vascular disease (CVD) of Increasing incidence
.

According to reports, compared with the general population, HIV-infected persons are twice as likely to develop atherosclerotic CVD

Infected heart blood vessels

However, the prevalence of aortic aneurysms in HIV-infected patients is still unclear
.

Julie et al investigated whether HIV status is independently associated with aortic aneurysm, and also assessed the risk factors associated with aortic aneurysm in HIV-infected patients

In the HIV infection study, 594 HIV-infected persons aged 40 and over were recruited, and 1188 age- and gender-matched non-infected controls were recruited from the general population study
.

According to the guidelines of the European Society of Cardiology, aortic aneurysm is defined as: aortic dilation ≥50% or subrenal aortic diameter ≥30 mm

594 HIV-infected persons 40 years and older 594 HIV-infected persons 40 years and older

Aortic aneurysm risk ratio between the two groups of subjects

Aortic aneurysm risk ratio between the two groups of subjects

The median ages of HIV-infected individuals and non-infected controls were 52 years (47-60) and 52 (48-61), respectively, and men accounted for 88% and 90%, respectively
.

46 aortic aneurysms were found in 42 (7.

46 aortic aneurysms were found in 42 (7.

Summary diagram

Summary diagram

In summary, compared with the uninfected control group, HIV-infected persons are four times more likely to develop aortic aneurysms, and HIV status is independently related to aortic aneurysm
.

Among HIV-infected persons, age, obesity, and hepatitis B infection are all associated with a higher incidence of aortic aneurysms

Compared with the uninfected control group, HIV-infected people are four times more likely to develop aortic aneurysm, and HIV status is independently associated with aortic aneurysm.

Original source:

Hogh Julie,Pham Michael Huy Cuong,Knudsen Andreas Dehlbok et al.

HIV infection is associated with thoracic and abdominal aortic aneurysms: a prospective matched cohort study in this message