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    Home > Active Ingredient News > Digestive System Information > Eur J Nutr: Eating dark roasted coffee reduces DNA damage in humans

    Eur J Nutr: Eating dark roasted coffee reduces DNA damage in humans

    • Last Update: 2020-07-11
    • Source: Internet
    • Author: User
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    The purpose of this study is to determine the protective effect of standard coffee drinks on DNA compared to water consumptiondesigned in parallel design singular, randomized controlled studies that included healthy women (n s 50) and men (n s 50) recruited in the general population of Central EuropeThe subjects were randomly divided into coffee and control groups, stratified by sex and body mass indexThe study included two four-week phases: a pretreatment phase that consumed at least 500 ml of water per day, but no coffee, tea, or any other caffeinated productDuring the subsequent intervention, the coffee group consumed 500 ml of freshly prepared dark roasted coffee mixture per day, while the control group consumed waterOn the last day of each period, blood is drawn and analyzed by comet analysis (single-cell gel electrophoresis) to assess the level of DNA damage (chain fracture)results showed that at the end of the dry expected, the average DNA chain fracture in the coffee group decreased compared to the control group (average difference of 0.23% TI (tail strength), p - 0.028)The average change (incremental value) of the coffee group compared to the baseline is -23% (p - 0.0012)The effect of drinking coffee is similar for men and womenDuring the intervention, neither group showed any significant change in weight or calorie intakein general, our results suggest that regular consumption of dark roasted coffee blends has a beneficial protective effect on the integrity of human DNA in both men and women
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