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    Home > Active Ingredient News > Infection > Eur Respir J: Effect of body mass index on the occurrence of non-tuberculosis mycobacteria lung disease.

    Eur Respir J: Effect of body mass index on the occurrence of non-tuberculosis mycobacteria lung disease.

    • Last Update: 2020-10-27
    • Source: Internet
    • Author: User
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    Worldwide, the incidence and prevalence of non-tuberculosis mycobacterial pulmonary disease (NTM-PD) is increasing.
    risk of NTT-PD among undernourished people may be higher.
    , researchers tried to clarify the effects of body mass index (BMI) and its changes on NTT-PD in a recent study published in Eur Respir J, an authoritative journal in the field of respiratory diseases.
    researchers conducted a retrospective study of Koreans older than 40 who underwent a two-yearly National Health Insurance System (NHIS) health check-up in 2005 and 2009 or 2006 and 2010.
    the researchers monitored eligible patients from the date of the study (NHIS health check-up dates are 2009 or 2010) until they were diagnosed with NCM-PD or December 31, 2017.
    the subjects in the group were classified according to BMI at the study start date.
    compared the annual incidence of NTT-PD per 100,000 people in the BMI group and the BMI variation group by calculating the risk ratio (HR).
    final analysis included a total of 5670,229 subjects.
    the rate of NTM-PD decreased with the increase of BMI compared to the subjects of BMI-lt;18.5 kg/m2: the subjects with a BMI of 18.5-22.9 adjusted HR (aHR) of 0.38 (95% confidence interval (CI) of 0.35-0.42) and for BMI of 2.42 Subjects 3-24.9 were 0.17 (0.15-0.19), 0.1 (0.09-0.11) for subjects with a BMI of 25-29.9, and 0.1 (0.07-0.13≥30 for BMI≥30.
    increased the occurrence of NTTM-PD by ≥1kg/m2 in 4 years (aHR was 1.08, 95% CI was 1.01-1.16), while BMI increased by ≥1 to reduce the occurrence of NTHM-PD (0.77, 95% CI was 0.71-0.83).
    , BMI was negatively associated with NTT-PD, and weight loss increased the risk of NPM-PD.
    .
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