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    Home > Active Ingredient News > Antitumor Therapy > European Radiology: About the malignantity of mumps lymphatic tissue-related lesions, let CT radiology tell you!

    European Radiology: About the malignantity of mumps lymphatic tissue-related lesions, let CT radiology tell you!

    • Last Update: 2021-02-24
    • Source: Internet
    • Author: User
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    Mucosal-related lymphatic tissue (MALT) lymphoma, or MALToma, is an epidural B-cell lymphoma that usually occurs in the stomach mucosa.
    , however, it can also develop in salivary glands, such as the mumps.
    benign lymphatic epithetic lesions (BLEL) are lymphatic hyperploids that also occur in the mumps and are usually classified as diffuse, atrophic, tumor-like and inflammatory.
    BLEL can be developed into MALToma through aggregation and proliferation processes.
    lymphoma was 44 times higher in patients with BLEL than in the general population.
    accurately identifying mumpsbleL and MALToma is critical to determining a patient's prognosmation and choosing the right treatment.
    radiology is a non-invasory, replicable and low-cost technique that can automatically extract comprehensive data from images, and has been widely used in tumor visible research.
    recently, a study published in the Journal of European Radiology developed and validated a preoperative radiological column map for preoperative identification of mumpsBLEL and MALToma, which combines CT radiological characteristics and clinical factors to provide clinical imaging for preoperative non-invasional assessment of mumps malignant lymphatic tissue lesions.
    study included 101 patients, including 46 BLEL cases and 55 MALToma cases, and divided the 101 patients into training sets (70 cases) and validation sets (31 cases).
    extract radiological features from flat-sweepING CT images, construct radiologic features, and calculate Radiology Scores (Rad-score).
    to evaluate demographic information and CT results to model clinical factors.
    radiological column chart using multivariate logic regression analysis method to combine Rad-score with independent clinical factors.
    evaluate and validate the performance levels of line diagrams, radiological features, and clinical models on training and validation datasets, and then compare them between the three models.
    seven features were used to construct radiologic features.
    radiological column charts combining clinical factors and radiological characteristics had good predictive value for the identification of mumpsBLEL and MALToma, with AAUCs for training and validation sets at 0.983 and 0.950, respectively.
    analysis of the decision curve shows that the column chart is superior to the clinical factor model in terms of clinical usefulness.
    Table Clinical Factor Model, Radiology Characteristics, and Diagnostic Performance Map Diagnostic Performance Map Clinical Factor Model, Radiology Group Features, and Radiological Group Line Map Subject Working Characteristics (ROC) Curves in Training Set (a) and Validation Set (b).
    this study developed and validated the first CT-based radiological column diagram for preoperative diagnosis of mumps tumor samples BLEL and MALToma.
    as a non-invasive quantitative imaging method, radiological column diagram can be used as an effective means to supplement the traditional imaging model in the course of clinical treatment.
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